Figure 3From: Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cellsCorrelative analysis of CREB and CREM binding site occupancy. A. Association of CREB, pol II and H3K4me3 in GC1-spg cells. Comparison of pol II and H3K4me3 tag density in the region of +/- 5 kb around the CREB-occupied loci. Clustering analysis identifies 3 classes, A; CREB loci with low or no pol II and H3K4me3, B-C; CREB loci with high pol II and H3K4me3 corresponding to transcription on the sense and anti-sense strands, respectively. B. Comparison of CREM tag density in the region of +/- 5 kb around the CREB-occupied loci. Clustering identifies 2 groups A; CREB loci with low or no CREM and B; CREB loci with high CREM. C. Venn diagramme comparing common and cell-specific CREB/CREM occupancy of binding sites using the CREB data in panel B and the equivalent analysis of the CREM occupied loci (data not shown).Back to article page