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Figure 3 | BMC Genomics

Figure 3

From: Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma

Figure 3

Senescence scoring in the NCI60 cell panel. Expression data from set GSE5846 were scored using (A) All markers from Table 1, (B) DAS markers, (C) mSS markers. Individual scores for each cell line are shown with cell lines separated according to tissue of origin. BR, breast cancer; CNS, central nervous system; CO, colorectal cancer; LC, lung cancer; LE, leukaemia; ME, melanoma; OV, ovarian cancer; PR, prostate cancer; RE, renal cancer. (D) Comparison of senescence scoring of public data for HT29 and DU145 cells with our experimental results.

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