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Table 2 Properties of Host and Target Genes

From: A potential role for intragenic miRNAs on their hosts' interactome

Property

Gene Set

Median[Range] Host/Target

Median[Range] Control

Ratio

p-Value

Total length (basepairs)

Host Genes

84871.0 [2792-2220381]

29324.5 [599-2304633]

2.89

< 2.2e-16

 

Target genes

83747.5 [2366-2220381]

30232.5 [218-2220381]

2.77

< 2.2e-16

Introns

Host Genes

13[1-88]

8[1-105]

1.62

4.3e-13

 

Target genes

10.5[0-78]

8[0-311]

1.31

9.77e-07

Length 5'UTR (basepairs)

Host Genes

279.5[0-385608]

298.5[0-1098107]

0.94

0.25

 

Target genes

439.5[0-460277]

282.5[0-1098107]

1.56

2.32e-08

Length 3'UTR (basepairs)

Host Genes

1218.5[0-535884]

872[0-321862]

1.4

4.71e-05

 

Target genes

1764[171-11799]

872[0-72058]

2.2

< 2.2e-16

ARE (absolute)

Host Genes

2.0[0-1794]

1.0[0-592]

2.0

3.89e-04

 

Target genes

5.0[0-47]

2.0[0-187]

2.5

< 2.2e-16

ARE (per kb)

Host Genes

1.9[0-2.74]

1.49[0-0.045]

1.26

0.012

 

Target genes

2.69[0-14.22]

1.63[0-76.92]

1.65

< 2.2e-16

5' UTR GC content

Host Genes

0.6[0.31-0.95]

0.59[0-1]

1.06

0.015

 

Target genes

0.59[0.26-1]

0.58[0-1]

1.01

0.71

  1. Host and target genes display similar properties, compared to a set of control genes, including increased length, higher number of total introns, longer 3'UTRs and higher frequency of "AU-rich elements" (AREs).