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Figure 3 | BMC Genomics

Figure 3

From: The cost of reducing starting RNA quantity for Illumina BeadArrays: A bead-level dilution experiment

Figure 3

The power to detect differential expression by quantity of starting RNA. Illustrating, for the analysis-group of bead-types, the increased ability to detect large log2-fold changes (for all levels of starting RNA), and how the relationship (between that ability and the size of the log-fold change) varies with the quantity of starting RNA. The empirical log fold change calculated from the 250 ng experiment is depicted on the x-axis, which is divided into 50 bins, each containing 2% of the bead-types (indicated by the vertical lines). On the y-axis are indicated 95% confidence intervals for the proportion of bead-types in each bin for which differential expression will be detected.

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