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Table 4 The ten most significant GO categories for genes with significant expression differences at each time point

From: Dynamic, mating-induced gene expression changes in female head and brain tissues of Drosophila melanogaster

Higher in mated females 0-2 hours post-mating

  

GO Term

P value

Number of genes

dopamine metabolic process

4.72E-04

2

anatomical structure development

9.53E-04

18

developmental process

1.26E-03

20

catecholamine metabolic process

2.04E-03

2

catechol metabolic process

2.05E-03

2

phenol metabolic process

2.05E-03

2

diol metabolic process

2.05E-03

2

multicellular organismal process

2.29E-03

22

system development

3.08E-03

15

positive regulation of multicellular organism growth

3.69E-03

2

Lower in mated females 0-2 hours post-mating

  

GO Term

P value

Number of genes

response to abiotic stimulus

2.18E-05

6

response to heat

9.81E-04

3

response to temperature stimulus

1.44E-03

3

alcohol metabolic process

1.66E-03

4

steroid catabolic process

3.17E-03

1

cholesterol catabolic process

3.18E-03

1

prenol metabolic process

3.19E-03

1

prenol biosynthetic process

3.20E-03

1

polyprenol metabolic process

3.20E-03

1

polyprenol biosynthetic process

3.21E-03

1

Higher in mated females 24 hours post-mating

  

GO Term

P value

Number of genes

response to light stimulus

5.95E-04

3

response to radiation

9.19E-04

3

absorption of visible light

1.98E-03

1

arginine catabolic process to glutamate

1.98E-03

1

positive regulation of biosynthetic process

2.68E-03

3

positive regulation of cellular biosynthetic process

2.68E-03

3

visual perception

2.86E-03

2

sensory perception of light stimulus

3.01E-03

2

positive regulation of cellular metabolic process

3.33E-03

3

positive regulation of metabolic process

3.47E-03

3

Lower in mated females 24 hours post-mating

  

GO Term

P value

Number of genes

small molecule metabolic process

3.61E-12

26

organic acid metabolic process

6.94E-11

16

carboxylic acid metabolic process

6.95E-11

16

oxoacid metabolic process

6.95E-11

16

cellular ketone metabolic process

2.16E-10

16

pentose-phosphate shunt

1.24E-07

4

NADP metabolic process

1.24E-07

4

NADPH regeneration

1.24E-07

4

nicotinamide metabolic process

7.35E-07

4

alkaloid metabolic process

7.37E-07

4

Higher in mated females 48 hours post-mating

  

GO Term

P value

Number of genes

phosphatidylserine metabolic process

2.23E-03

1

phosphatidylserine biosynthetic process

2.24E-03

1

male courtship behavior

2.25E-03

1

arginine catabolic process to glutamate

2.25E-03

1

D-ribose metabolic process

4.55E-03

1

arginine catabolic process

4.57E-03

1

mating behavior, sex discrimination

4.57E-03

1

cellular process

9.92E-01

8

Lower in mated females 48 hours post-mating

  

GO Term

P value

Number of genes

small molecule metabolic process

1.40E-12

26

organic acid metabolic process

4.52E-10

15

carboxylic acid metabolic process

4.54E-10

15

oxoacid metabolic process

4.54E-10

15

cellular ketone metabolic process

1.31E-09

15

hexose metabolic process

7.43E-09

9

monosaccharide metabolic process

2.86E-08

9

pentose-phosphate shunt

1.10E-07

4

NADP metabolic process

1.10E-07

4

NADPH regeneration

1.10E-07

4

Higher in mated females 72 hours post-mating

  

GO Term

P value

Number of genes

phosphatidylserine metabolic process

3.14E-03

1

phosphatidylserine biosynthetic process

3.14E-03

1

leucyl-tRNA aminoacylation

6.34E-03

1

asparagine metabolic process

6.37E-03

1

asparagine biosynthetic process

6.37E-03

1

organic acid metabolic process

7.63E-03

4

carboxylic acid metabolic process

7.67E-03

4

oxoacid metabolic process

7.67E-03

4

biological regulation

9.97E-01

2

Lower in mated females 72 hours post-mating

  

GO Term

P value

Number of genes

oxidation reduction

8.05E-06

13

organic acid metabolic process

3.75E-05

9

carboxylic acid metabolic process

3.76E-05

9

oxoacid metabolic process

3.76E-05

9

aspartate metabolic process

4.36E-05

2

cellular ketone metabolic process

6.82E-05

9

purine base biosynthetic process

2.61E-04

2

glutamate biosynthetic process

4.35E-04

2

small molecule metabolic process

5.26E-04

13

'de novo' IMP biosynthetic process

6.53E-04

2