Table 2 Genes with Gene Ontology annotation 'positive regulation of transcription, DNA-dependent' significantly regulated in zebrafish gill by zinc supplementation for 8 h to 14 days as indicated.
From: Dynamic transcriptomic profiles of zebrafish gills in response to zinc supplementation
Time point | Unigene ID | Gene Description | Gene symbol | Human homologuea | Reg.b |
|---|---|---|---|---|---|
8 h | Dr.75386 | Hypothetical protein LOC100001897 (LOC100001897) | LOC100001897 | THRAP1 | ↑ |
|  | Dr.113555 | Hip2 | hip2 | HIP2 | ↓ |
|  | Dr.82162 | Polymerase (RNA) II (DNA directed) polypeptide E (polr2e) | polr2e | POLR2E | ↓ |
|  | Dr.99315 | GLI-Kruppel family member GLI3 (gli3) | gli3 | GLI3 | ↓ |
|  | Dr.80037 | TAR (HIV) RNA binding protein 2 (tarbp2) | tarbp2 | TARBP2 | ↓ |
|  | Dr.27060 | Nuclear receptor subfamily 1, group I, member 2 (nr1i2) | nr1i2 | NR1I2 | ↓ |
24 h | Dr.52129 | Similar to Pax-family transcription factor 6.2 (LOC557147) | LOC557147 | PAX6 | ↑ |
|  | Dr.81306 | GATA-binding protein 4 (gata4) | gata4 | GATA4 | ↑ |
|  | Dr.1064 | V-jun sarcoma virus 17 oncogene homolog (avian) (jun) | Jun | JUN | ↑ |
|  | Dr.76866 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (Smarcc1) | smarcc1 | SMARCC1 | ↑ |
|  | Dr.82597 | Homeo box A2b (hoxa2b) | hoxa2b | HOXA2 | ↑ |
|  | Dr.134300 | Si:ch211-239e6.3 (si:ch211-239e6.3) | ppara | PPARA | ↑ |
|  | Dr.82680 | Sal-like 1a (Drosophila) (sall1a) | sall1a | SALL1 | ↑ |
|  | Dr.76928 | MAD homolog 1 (Drosophila) (smad1) | smad1 | SMAD1 | ↑ |
|  | Dr.42859 | Zgc:165628 (LOC560054) | zgc:165628 | BCL11B | ↑ |
|  | Dr.29 | Cyclin E (ccne) | ccne | CCNE1 | ↑ |
|  | Dr.81131 | Wu:fj43h12 (wu:fj43h12) | wu:fj43h12 | DPF2 | ↑ |
|  | Dr.119569 | Estrogen receptor 1 (esr1) | esr1 | ESR1 | ↓ |
|  | Dr.13792 | Zgc:55307 (zgc:55307) | zgc:55307 | NCOA4 | ↓ |
|  | Dr.108093 | Forkhead box P1a (foxp1a) | foxp1a | FOXP1 | ↓ |
|  | Dr.79098 | Methyl-CpG binding domain protein 1 (mbd1) | mbd1 | MBD1 | ↓ |
|  | Dr.41031 | Similar to MGC86299 protein (LOC564317) | LOC564317 | SMARCD2 | ↓ |
|  | Dr.78256 | Influenza virus NS1A binding protein a (ivns1abpa) | ivns1abpa | IVNS1ABP | ↓ |
|  | Dr.76084 | Si:dkey-261h15.1 (LOC569156) | Si:dkey-261h15.1 | HIPK3 | ↓ |
|  | Dr.81949 | Zgc:77060 (zgc:77060) | zgc:77060 | NFIL3 | ↓ |
4 d | Dr.82517 | Homeo box (H6 family) 3 (hmx3) | hmx3 | HMX3 | ↑ |
|  | Dr.79439 | NK2 transcription factor related, locus 9 (Drosophila) (nkx2.9) | nkx2.9 | NKX2-8 | ↑ |
|  | Dr.132864 | Wilms tumor 1a (wt1a) | wt1a | WT1 | ↑ |
|  | Dr.78569 | Zinc finger homeobox 1 (zfhx1) | zfhx1 | TCF8 | ↑ |
|  | Dr.351 | Retinoid × receptor, beta a (rxrba) | rxrba | RXRA | ↑ |
|  | Dr.334 | Orthodenticle homolog 2 (otx2) | otx2 | OTX2 | ↑ |
|  | Dr.8104 | Nuclear receptor subfamily 6, group A, member 1a (nr6a1a) | nr6a1a | NR6A1 | ↑ |
|  | Dr.83684 | Iroquois homeobox protein 5 (irx5a) | irx5a | IRX5 | ↑ |
|  | Dr.75342 | Similar to sal-like 4 (sb:cb372) | sall4 | SALL4 | ↓ |
7 d | Dr.1467 | Paired box gene 9 (pax9) | pax9 | PAX9 | ↑ |
|  | Dr.77524 | GATA-binding protein 3 (gata3) | gata3 | GATA3 | ↑ |
|  | Dr.84720 | Zgc:110646 (zgc:110646) | zgc:110646 | MED4 | ↑ |
|  | Dr.132502 | Homeo box B3a (hoxb3a) | hoxb3a | HOXB3 | ↑ |
|  | Dr.119956 | Zgc:103566 (zgc:103566) | irf11 | IRF1 | ↑ |
|  | Dr.356 | GATA-binding protein 2 (gata2) | gata2 | GATA2 | ↑ |
|  | Dr.120105 | Signal transduction and activation of transcription 1 (stat1) | stat1a | STAT1 | ↑ |
|  | Dr.2 | Distal-less homeobox gene 2a (dlx2a) | dlx2a | DLX2 | ↑ |
|  | Dr.39148 | Zgc:158606 (zgc:158606) | zgc:158441 | FBXL11 | ↑ |
|  | Dr.75088 | POU domain gene 50 (pou50) | pou50 | POU3F1 | ↑ |
|  | Dr.80575 | C20orf24 homolog (human) (c20orf24) | c20orf24 | C20orf24 | ↓ |
|  | Dr.16181 | Zgc:77260 (zgc:77260) | zgc:77260 | NR2F6 | ↓ |
|  | Dr.78322 | Similar to Epidermal Langerhans cell protein LCP1 (LOC559853) | LOC559853 | C14ORF92 | ↓ |
|  | Dr.719 | DR1-associated protein 1 (negative cofactor 2 alpha) (drap1) | drap1 | DRAP1 | ↓ |
|  | Dr.7307 | Metastasis associated 1 family, member 2 (mta2) | mta2 | MTA2 | ↓ |
|  | Dr.21307 | SET and MYND domain containing 1a (smyd1a) | smyd1a | SMYD1 | ↓ |
|  | Dr.15663 | CCAAT/enhancer binding protein (C/EBP), gamma (cebpg) | cebpg | CEBPG | ↓ |
14 d | Dr.76961 | Zgc:158157 (zgc:158157) | zgc:158157 | DIDO1 | ↑ |
|  | Dr.6047 | Zgc:73112 (zgc:73112) | zgc:73112 | PYCR1 | ↑ |
|  | Dr.133831 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 (ctdp1) | ctdp1 | CTDP1 | ↑ |
|  | Dr.78697 | Zgc:91808 (zgc:91808) | rfx2 | RFX2 | ↑ |