Figure 1

Comparison of gene expression profiles following 13 and 52 week exposure to TCDD, PCB126 or PCB153. Venn diagram depicting the number of genes shared by the hepatic gene expression profiles in female Sprague-Dawley rats following 13 weeks and 52 weeks of exposure to 100 ng/kg/day TCDD, 1000 ng/kg/day PCB126 or 1000 μg/kg/day PCB153. In parenthesis is the total number of significantly different genes differentially expressed for each exposure group. Genes were deemed significantly different if they expressed a ≥2-fold change in expression and a p-value ≤ 0.05 as determined by student t-test analysis.