Table 3 Relative fold change in 16 genes differentially expressed in livers of female Sprague-Dawley rats following 52 weeks of chronic p.o. exposure to 30 ng, 300 ng and 1000 ng/kg/day PCB126

NM_012540

Cyp1a1^a

Cytochrome P450, family 1, subfamily a, polypeptide 1

499*

1263*

1551*

NM_012940

Cyp1b1^a

Cytochrome P450, family 1, subfamily b, polypeptide 1

18

866*

2091*

NM_173339

Ceacam10^b

CEA-related cell adhesion molecule 10

17

660*

976*

NM_031530

Ccl2

Chemokine (C-C motif) ligand 2

5

11

31*

NM_001039691///NM_057105

Ugt1a6^a

UDP glycosyltransferase 1 family, polypeptide A6

3

11*

16*

NM_130407

Ugt1a7^a

UDP glycosyltransferase 1 family, polypeptide A7

3

23*

40*

NM_017127

Chka

Choline kinase alpha

2

7*

6*

NM_012656

Sparc

Secreted acidic cysteine rich glycoprotein

2

2

4*

NM_031569///NM_057098///XM_001055907///XM_345486

Oprl1///Tcea2

Opioid receptor-like 1///Transcription elongation factor A (SII), 2

2

4

4*

NM_024127

Gadd45a

Growth arrest and DNA-damage-inducible 45 alpha

2

4

4*

NM_012600

Me1

Malic enzyme 1

2

2*

4*

NM_001037979

Adipor2^b

Adiponectin receptor 2

-3

-2

-6*

NM_012672

Thrb

Thyroid hormone receptor beta

-3

-3

-3*

NM_032071

Synj2

Synaptojanin 2

-3

-3

-4*

XM_001071608///XM_213849

Nfix

Nuclear factor I/X

-3

-3

-5*

NM_012988

Nfia

Nuclear factor I/A

-4

-4

-3*