Figure 8

Experimental antimicrobial resistance (AMR) screening among test isolates (A) and theoretical assessment of AMR in isolates with recently published genome (B). Colours in the left plot indicate posterior probabilities of membership to the signal fraction of the overall distribution of AMR-related hybridisation intensities. Additionally, the validation of disc diffusion tests is mapped on the microarray results. In case of consistency between microarray and disc diffusion results, the red colour scale is used, while the blue scale indicates no consistency. Yellow bars signify resistance in disc diffusion which was not detected by microarray analysis. Test hybridisations of pure culture DNA are plotted against AMR probes (right axis labels) while the type of AMR is provided as axis labels on the right. Colours of matrix B indicate the length of longest consecutive matches obtained by Smith-Waterman alignments of AMR probes against genome sequences.