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Table 2 Selected GO category and genes that are altered at 35 days, and comparison with changes at 7 days.

From: Differential alterations in gene expression profiles contribute to time-dependent effects of nandrolone to prevent denervation atrophy

GO category Gene Name Gene Symbol 35 days 7 days
    (Nan vs Veh) (Nan vs Veh)
Calcium/calmodulin-mediated signaling Regulator of Calcineurin 2 (Down syndrome critical region gene 1-like 1) RCAN2 -1.69 1.26
  Calcium/calmodulin-dependent protein kinase II, alpha Camk2a -3.23 -1.30
  Calcineurin B, type1 Ppp3r1 2.11 1.12
Cell cycle G0/G1 switch gene 2 G0s2 2.07 -1.45
  Transducer of ERBB2, 2 Tob2 -1.43 1.03
Cell proliferation Protein phosphatase 1, catalytic subunit, beta isoform PPP1CB -1.92 1.02
  EGL nine homolog 3 EGLN3 -1.64 1.12
Development Clusterin Clu 2.52 1.05
  Developmentally regulated GTP binding protein 1 Drg1 3.97 1.24
  Dicer1 Dicer1 -2.00 -1.14
  Sortilin 1 SORT1 -1.82 1.50
G-protein coupled receptor protein signaling pathway Regulator of G-protein signaling 2 RGS2 1.96 1.08
  Guanine nucleotide binding protein, alpha 12 GNA12 1.94 1.07
  GNAS complex locus GNAS -2.38 1.24
Growth factor Apolipoprotein D Apo D 14.73 3.00
  Osteoglycin OGN 2.60 1.27
Muscle development Myotrophin Mtpn 1.92 1.02
  AE binding protein 1 AEBP1 3.44 2.60
Muscle contraction Myosin binding protein H Mybph -1.82 1.15
Nervous system development Myelin basic protein MBP 12.06 2.85
Protein kinase Protein kinase, AMP-activated, gamma 3 non-catalytic subunit Prkag3 -1.64 1.05
  Protein kinase inhibitor, alpha Pkiα 2.47 -1.08
  Protein kinase, AMP-activated, a1 catalytic unit Prkaa1 1.93 -1.14
  Sprouty protein with EVH-1 domain 1, related sequence SPRED1 2.93 1.58
Response to wounding Chemokine (C-C motif) ligand 7 CCL7 1.70 1.05
  Chemokine (C-C motif) receptor 1 CCR1 1.55 1.23
Transcription Early growth response 1 Egr1 2.28 -2.33
  Early growth response 2 Erg2 2.54 -3.85
  Early growth response 3 Egr3 2.29 -4.76
  Forkhead box protein O1A FOXO1 -2.22 1.22
  Transforming, acidic coiled-coil containing protein 2 TACC2 -2.38 1.41
  Nuclear protein 1 Nupr1 2.17 1.37
  Heat shock transcription factor 4 HSF4 -1.72 1.10
  carboxy-terminal domain, RNA polymerase II, polypeptide A Ctdsp1 -1.54 1.06
  Grainyhead-like 1 Grhl1 -2.70 1.22
  Human immunodeficiency virus type I enhancer binding protein 1 HIV EP1 1.72 1.16
  TSC22-related-inducible leucine zipper protein 2 TSC22 -1.19 2.30
Translation Eukaryotic elongation factor-2 kinase Eef2k -2.44 1.24
  DNA-damage-inducible transcript 4-like REDD2/DDIT4L -1.72 -1.32
Ubiquitin -Proteasome Pathway Sequestosome 1 SQSTM1 -1.92 1.37
  UBIQUITIN-CONJUGATING ENZYME E2H Ube2h 1.97 1.12
Wnt signaling pathway Casein kinase 1, alpha 1 Csnk1a1 -2.44 -1.37
  1. Abbreviations: Nandrolone, Nan; Vehicle, Veh.