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Table 3 Selected GO category and genes that are altered at 35 days denervation, in comparison with 7 days denervation

From: Differential alterations in gene expression profiles contribute to time-dependent effects of nandrolone to prevent denervation atrophy

GO category Gene Name Gene Symbol Fold-Change (35 vs 7)
Transcriptional Coregulators creb binding protein CREBBP 3.98
  rna-binding region (rnp1, rrm) containing 2 RNPC2 2.85
  paired related homeobox 1 PRRX1 2.40
  nuclear receptor interacting protein 1 (predicted) Nrip1 2.06
  n-myc (and stat) interactor NMI 2.00
  homeodomain interacting protein kinase 2 (predicted) Hipk2 -2.54
  tg interacting factor Tgif -2.75
  lim and cysteine-rich domains 1 (predicted) Lmcd1 -4.27
  Ankyrin repeat domain 1 (cardiac muscle) Ankrd1 -4.48
  Ankyrin repeat domain 2 (stretch responsive muscle) Ankrd2 -23.81
Transcription Factors and Other Transcriptional Regulators    
  TSC22 domain family, member 4 TSC22D4 3.28
  basic helix-loop-helix family, member e41 BHLHB3 3.17
  D site of albumin promoter (albumin D-box) binding protein DBP 3.07
  activating transcription factor 5 ATF5 2.53
  MAX gene associated MGA (includes EG:23269) 2.40
  myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) MLL 2.38
  POZ (BTB) and AT hook containing zinc finger 1 PATZ1 2.34
  Kruppel-like factor 5 (intestinal) KLF5 2.25
  thyrotrophic embryonic factor TEF 2.25
  single-minded homolog 2 (Drosophila) SIM2 2.16
  TSC22 domain family, member 3 TSC22D3 2.10
  myogenic differentiation 1 MYOD1 2.10
  Kruppel-like factor 15 KLF15 2.05
  CCAAT/enhancer binding protein (C/EBP), delta CEBPD 2.05
  polycomb group ring finger 6 PCGF6 -2.08
  SRY (sex determining region Y)-box 4 SOX4 -2.13
  v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) MAFF -2.33
  zinc finger protein 367 ZNF367 -2.67
  Ankyrin repeat and SOCS box-containing 5 ASB5 -2.95
  aryl hydrocarbon receptor nuclear translocator-like ARNTL -3.07
  LIM and cysteine-rich domains 1 LMCD1 -4.27
  regulator of calcineurin 1 RCAN1 -5.05
  BTG family, member 2 BTG2 -5.35
  early growth response 2 (Krox-20 homolog, Drosophila) Egr2 -6.85
Kinases v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) ERBB2 4.08
  neurotrophic tyrosine kinase, receptor, type 2 NTRK2 3.33
  phosphoinositide-3-kinase, class 2, beta polypeptide PIK3C2B 2.50
  cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial CMPK2 2.43
  discoidin domain receptor tyrosine kinase 2 DDR2 2.33
  activin A receptor, type IIB ACVR2B 2.28
  protein kinase, cAMP-dependent, regulatory, type II, beta PRKAR2B 2.08
  EPH receptor B3 EPHB3 1.94
  cell division cycle 2-like 6 (CDK8-like) CDC2L6 1.93
  protein kinase, AMP-activated, beta 2 non-catalytic subunit PRKAB2 1.89
  PTEN induced putative kinase 1 PINK1 1.81
  STE20-related kinase adaptor beta STRADB -1.87
  mex-3 homolog B (C. elegans) MEX3B -1.92
  RIO kinase 3 (yeast) RIOK3 -2.32
  tribbles homolog 1 (Drosophila) TRIB1 -2.45
  uridine-cytidine kinase 2 UCK2 -2.56
  membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) MPP6 -2.84
Phosphatases protein tyrosine phosphatase, receptor type, D PTPRD 6.96
  dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) DUSP11 -1.54
  protein phosphatase 1, regulatory (inhibitor) subunit 3C PPP1R3C -1.84
  protein phosphatase 1J (PP2C domain containing) PPM1J -1.91
  protein tyrosine phosphatase, receptor type, C PTPRC -2.21
  protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A PTPLA -2.95
  nudix (nucleoside diphosphate linked moiety X)-type motif 4 NUDT4 -3.62