Table 3 Selected GO category and genes that are altered at 35 days denervation, in comparison with 7 days denervation
GO category | Gene Name | Gene Symbol | Fold-Change (35 vs 7) |
|---|---|---|---|
Transcriptional Coregulators | creb binding protein | CREBBP | 3.98 |
| Â | rna-binding region (rnp1, rrm) containing 2 | RNPC2 | 2.85 |
| Â | paired related homeobox 1 | PRRX1 | 2.40 |
| Â | nuclear receptor interacting protein 1 (predicted) | Nrip1 | 2.06 |
| Â | n-myc (and stat) interactor | NMI | 2.00 |
| Â | homeodomain interacting protein kinase 2 (predicted) | Hipk2 | -2.54 |
| Â | tg interacting factor | Tgif | -2.75 |
| Â | lim and cysteine-rich domains 1 (predicted) | Lmcd1 | -4.27 |
| Â | Ankyrin repeat domain 1 (cardiac muscle) | Ankrd1 | -4.48 |
| Â | Ankyrin repeat domain 2 (stretch responsive muscle) | Ankrd2 | -23.81 |
Transcription Factors and Other Transcriptional Regulators | Â | Â | Â |
| Â | TSC22 domain family, member 4 | TSC22D4 | 3.28 |
| Â | basic helix-loop-helix family, member e41 | BHLHB3 | 3.17 |
| Â | D site of albumin promoter (albumin D-box) binding protein | DBP | 3.07 |
| Â | activating transcription factor 5 | ATF5 | 2.53 |
| Â | MAX gene associated | MGA (includes EG:23269) | 2.40 |
| Â | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | MLL | 2.38 |
| Â | POZ (BTB) and AT hook containing zinc finger 1 | PATZ1 | 2.34 |
| Â | Kruppel-like factor 5 (intestinal) | KLF5 | 2.25 |
| Â | thyrotrophic embryonic factor | TEF | 2.25 |
| Â | single-minded homolog 2 (Drosophila) | SIM2 | 2.16 |
| Â | TSC22 domain family, member 3 | TSC22D3 | 2.10 |
| Â | myogenic differentiation 1 | MYOD1 | 2.10 |
| Â | Kruppel-like factor 15 | KLF15 | 2.05 |
| Â | CCAAT/enhancer binding protein (C/EBP), delta | CEBPD | 2.05 |
| Â | polycomb group ring finger 6 | PCGF6 | -2.08 |
| Â | SRY (sex determining region Y)-box 4 | SOX4 | -2.13 |
| Â | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | MAFF | -2.33 |
| Â | zinc finger protein 367 | ZNF367 | -2.67 |
| Â | Ankyrin repeat and SOCS box-containing 5 | ASB5 | -2.95 |
| Â | aryl hydrocarbon receptor nuclear translocator-like | ARNTL | -3.07 |
| Â | LIM and cysteine-rich domains 1 | LMCD1 | -4.27 |
| Â | regulator of calcineurin 1 | RCAN1 | -5.05 |
| Â | BTG family, member 2 | BTG2 | -5.35 |
| Â | early growth response 2 (Krox-20 homolog, Drosophila) | Egr2 | -6.85 |
Kinases | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | ERBB2 | 4.08 |
| Â | neurotrophic tyrosine kinase, receptor, type 2 | NTRK2 | 3.33 |
| Â | phosphoinositide-3-kinase, class 2, beta polypeptide | PIK3C2B | 2.50 |
| Â | cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial | CMPK2 | 2.43 |
| Â | discoidin domain receptor tyrosine kinase 2 | DDR2 | 2.33 |
| Â | activin A receptor, type IIB | ACVR2B | 2.28 |
| Â | protein kinase, cAMP-dependent, regulatory, type II, beta | PRKAR2B | 2.08 |
| Â | EPH receptor B3 | EPHB3 | 1.94 |
| Â | cell division cycle 2-like 6 (CDK8-like) | CDC2L6 | 1.93 |
| Â | protein kinase, AMP-activated, beta 2 non-catalytic subunit | PRKAB2 | 1.89 |
| Â | PTEN induced putative kinase 1 | PINK1 | 1.81 |
| Â | STE20-related kinase adaptor beta | STRADB | -1.87 |
| Â | mex-3 homolog B (C. elegans) | MEX3B | -1.92 |
| Â | RIO kinase 3 (yeast) | RIOK3 | -2.32 |
| Â | tribbles homolog 1 (Drosophila) | TRIB1 | -2.45 |
| Â | uridine-cytidine kinase 2 | UCK2 | -2.56 |
| Â | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) | MPP6 | -2.84 |
Phosphatases | protein tyrosine phosphatase, receptor type, D | PTPRD | 6.96 |
| Â | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | DUSP11 | -1.54 |
| Â | protein phosphatase 1, regulatory (inhibitor) subunit 3C | PPP1R3C | -1.84 |
| Â | protein phosphatase 1J (PP2C domain containing) | PPM1J | -1.91 |
| Â | protein tyrosine phosphatase, receptor type, C | PTPRC | -2.21 |
| Â | protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A | PTPLA | -2.95 |
| Â | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | NUDT4 | -3.62 |