Structural modelling and comparative analysis of homologous, analogous and specific proteins from Trypanosoma cruzi versus Homo sapiens: putative drug targets for chagas' disease treatment

Table 5 List of modelled sequences classified by AnEnΠ as analogous or specific of Trypanosoma cruzi, in relation to Homo sapiens.

Categories	Quality Models	EC^a	Description^b
A. Analogous	4	1.3.1.34	2,4-dienoyl-CoA reductase(NADPH) (ID^c: Tc00.1047053509941.100)
	5	1.3.1.34	2,4-dienoyl-CoA reductase(NADPH) (ID^c: Tc00.1047053510303.210)
	6	3.1.1.3	Triacylglycerol lipase (ID^c: Tc00.1047053509005.50)
B. Specific ofT. cruzi	1	1.8.1.12	Trypanothione-disulfide reductase (ID^c: Tc00.1047053503555.30)
	3	1.8.1.12	Trypanothione-disulfide reductase (ID^c: Tc00.1047053504507.5)
	4	2.5.1.47	Cysteine synthase (ID^c: Tc00.1047053507165.50, Tc00.1047053507793.20)
	3	3.4.22.51	Cruzipain (ID^c: Tc00.1047053508595.50, Tc00.1047053507297.10)
	6	3.4.22.51	Cruzipain (ID^c: Tc00.1047053506529.550, Tc00.1047053507537.20)
	7	3.4.22.51	Cruzipain (ID^c: Tc00.1047053509429.320, Tc00.1047053507603.260, Tc00.1047053507603.270, Tc00.1047053509401.30)
	5	3.6.3.6	Proton-exporting ATPase (ID^c: Tc00.1047053506649.20)
	6	3.6.3.6	Proton-exporting ATPase (ID^c: Tc00.1047053505763.19)
	4	3.4.24.36	Leishmanolysin (ID^c: Tc00.1047053511211.90, Tc00.1047053510565.150, Tc00.1047053507623.110, Tc00.1047053508699.100, Tc00.1047053508699.90, Tc00.1047053509011.80, Tc00.1047053506587.100, Tc00.1047053509205.100, Tc00.1047053506163.10, Tc00.1047053506163.20, Tc00.1047053508813.40, Tc00.1047053505965.10, Tc00.1047053506257.50, Tc00.1047053510899.10, Tc00.1047053505931.10, Tc00.1047053505931.20, Tc00.1047053511203.10, Tc00.1047053504397.20, Tc00.1047053506921.10, Tc00.1047053508475.30, Tc00.1047053505615.10, Tc00.1047053508825.10, Tc00.1047053510873.20, Tc00.1047053507197.10)

ISSN: 1471-2164