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Table 1 Identification of sex-biased genes in five tissues

From: Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse

  # Arrays # Genes # Genes on Sex Chr
Tissue Females Males Total Female up Male up X Obs X Exp p Y Obs Y Exp p
A. Striatum 43 43 173 35 138 15 6.3 * 4 0.29 *
   Neocortex 43 43 19 9 10 7 0.66 ** 8 0.03 ***
B. Hippocampus 60 60 12 8 4 8 0.4 *** 4 0.008 ***
   Eye 60 60 31 21 10 12 1 *** 5 0.021 ***
   Lung 22 22 160 101 59 16 5.4 ** 5 0.11 ***
   Total 228 228          
  1. A: Tissues analysed using Illumina 6v1.1 platform.
  2. B: Tissues analysed using Affymetrix M430v2.0 platform.
  3. # Arrays: Number of arrays used for each tissue and sex.
  4. # Genes: Number of significant sex-biased genes in each tissue and sex. Selection criteria: Wilcoxon Mann-Whitney test followed by Benjamini-Hochberg (B-H) correction for multiple testing. B-H adjusted threshold p ≤ 0.05. Unannotaded probes and gene-probe redundancies are not included in these numbers; Additional file 1 includes all significant probes and raw p-values.
  5. # Genes on Sex Chr: Observed number of genes on the sex chromosomes and expected numbers when "# Genes Total" are drawn from the array. Asterisks denote that X- and Y-linkage is statistically overrepresented among sex-biased genes according to Fisher's exact test. p-values: * ≤ 1E-3, ** ≤ 1E-10, *** ≤ 1E-15.