| # Arrays | # Genes | # Genes on Sex Chr |
---|
Tissue | Females | Males | Total | Female up | Male up | X Obs | X Exp | p | Y Obs | Y Exp | p |
---|
A. Striatum
| 43 | 43 | 173 | 35 | 138 | 15 | 6.3 | * | 4 | 0.29 | * |
   Neocortex | 43 | 43 | 19 | 9 | 10 | 7 | 0.66 | ** | 8 | 0.03 | *** |
B. Hippocampus | 60 | 60 | 12 | 8 | 4 | 8 | 0.4 | *** | 4 | 0.008 | *** |
   Eye | 60 | 60 | 31 | 21 | 10 | 12 | 1 | *** | 5 | 0.021 | *** |
   Lung | 22 | 22 | 160 | 101 | 59 | 16 | 5.4 | ** | 5 | 0.11 | *** |
   Total | 228 | 228 |  |  |  |  |  |  |  |  |  |
- A: Tissues analysed using Illumina 6v1.1 platform.
- B: Tissues analysed using Affymetrix M430v2.0 platform.
- # Arrays: Number of arrays used for each tissue and sex.
- # Genes: Number of significant sex-biased genes in each tissue and sex. Selection criteria: Wilcoxon Mann-Whitney test followed by Benjamini-Hochberg (B-H) correction for multiple testing. B-H adjusted threshold p ≤ 0.05. Unannotaded probes and gene-probe redundancies are not included in these numbers; Additional file 1 includes all significant probes and raw p-values.
- # Genes on Sex Chr: Observed number of genes on the sex chromosomes and expected numbers when "# Genes Total" are drawn from the array. Asterisks denote that X- and Y-linkage is statistically overrepresented among sex-biased genes according to Fisher's exact test. p-values: * ≤ 1E-3, ** ≤ 1E-10, *** ≤ 1E-15.