Genes optimized by evolution for accurate and fast translation encode in Archaea and Bacteria a broad and characteristic spectrum of protein functions

Table 1 Abundance of functional categories (FunCat level 1) in archaeal and bacterial effectomes

		Archaea			Bacteria
FunCat Category	Description	#_Eff( Cat )	#_All( Cat )	Abund _Eff	#_Eff( Cat )	#_All( Cat )	Abund _Eff
1	Metabolism	594	15495	-0.21	15948	461317	-0.24
2	Energy	110	1508	0.07	5129	47263	0.25
10	Cell cycle and DNA processing	30	2557	-0.73	1775	116118	-0.60
11	Transcription	32	2746	-0.73	2587	105731	-0.39
12	Protein synthesis	1006	3576	0.65	29446	67653	0.86
14	Protein fate (folding, modification, destination)	91	2106	-0.16	2502	71643	-0.24
18	Regulation of metabolism and protein function	8	395	-0.48	61	8494	-0.95
20	Cellular transport, transport facilitation and transport routes	160	3798	-0.17	5551	155592	-0.23
30	Cellular communication/signal transduction mechanism	0	931	-2.23	138	37418	-1.22
32	Cell rescue, defense and virulence	27	590	-0.13	1026	24273	-0.16
34	Interaction with the environment	21	548	-0.21	1059	26204	-0.17
38	Transposable elements, viral and plasmid proteins	0	68	-	23	5107	-1.13
40	Cell fate	0	9	-	76	6919	-0.72
41	Development (systemic)	0	2	-	3	385	-0.30
42	Biogenesis of cellular components	13	1235	-0.77	1271	83665	-0.60
70	Subcellular localization	191	3511	-0.06	8601	175358	-0.09
	Sum:	2283	39075		75196	1393140

For archaeal and bacterial genomes, the number of gene products contributing to FunCat categories was determined. The column labeled #_All(Cat) gives the number of genes deduced from the whole dataset. The column labeled #_Eff(Cat) gives the number of genes belonging to the respective effectomes. The column Abund_Efflists the ratio log(f_Eff(Cat)/f_All(Cat)) for the category, if #_All(Cat) was at least 100. In all other cases a trend is given indicated by a "-" for underrepresentation. The line labeled Sum lists the number of genes being analyzed.

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