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Table 2 DEGseq analysis of marker genes as well as those highlighted in this study related to digit development

From: Digital gene expression tag profiling of bat digits provides robust candidates contributing to wing formation

Genes Tag raw counts Hand DII-V vs. Hand DI Hand DII-V vs. Foot Hand DI vs. Foot
  Hand DII-V Hand DI Foot log2(Fold_change) normalized p-value log2(Fold_change) normalized p-value log2(Fold_change) normalized p-value
Marker genes       
Tbx5 175 134 6* 0.326 0.048 5.6385 1.04E-57 5.3125 1.81E-45
Pitx1 6 9 354* -0.6441 0.3921 -5.1104 4.08E-67 -4.4663 3.04E-63
Meis2 b 73* 12 18 2.5457 1.13E-11 2.7922 5.00E-17 0.2465 0.6365
Hoxd10 b 61* 3 10 4.2866 1.09E-14 3.3811 5.17E-17 -0.9056 0.289
Krt17 ab 68* 267 455 -2.3284 2.28E-40 -1.9474 4.40E-38 0.381 0.0003
Elongated digits       
Tbx3 b 118* 21 39 2.4312 4.16E-17 2.3695 2.10E-22 -0.0617 0.8689
Tbx15 b 171* 41 89 2.0011 2.79E-19 1.7144 2.10E-21 -0.2868 0.2648
Bmp3 b 19* 2 5 3.1888 1.04E-04 2.6983 2.64E-05 -0.4905 0.6626
Rgmb b 727* 133 289 2.3914 5.76E-95 2.1031 8.28E-112 -0.2882 0.0435
Smad1 264* 122 250 1.0545 4.34E-12 0.8509 1.01E-11 -0.2036 0.1782
Smad4 412* 244 351 0.6966 1.19E-09 1.0034 1.60E-22 0.3068 0.0086
Nog a 5** 17 44 -2.1207 1.53E-03 -2.3427 6.61E-06 -0.2219 0.5543
Hoxd8 19* 1 4 4.1888 1.81E-05 3.0202 8.64E-06 -1.1686 0.4084
Hoxd9 45* 10 13 2.1108 1.88E-06 2.5637 3.17E-10 0.4529 0.4442
Satb1 397* 117 286 1.7035 1.48E-34 1.2454 3.85E-30 -0.4581 0.0019
Hoxa1 b 61* 14 12 2.0642 4.50E-08 3.118 5.91E-16 1.0538 0.0577
Twist1 b 2521* 809 1767 1.5806 7.26E-189 1.285 4.31E-191 -0.2957 3.08E-07
Tmeff2 b 95* 22 50 2.0513 1.06E-11 1.6983 2.01E-12 -0.353 0.3091
Enpp2 b 27* 0 6 5.6957 8.71E-08 2.9422 1.64E-07 -2.7535 0.0698
Thumb &Foot       
Tbx4 ab 20* 102 390 -2.7057 3.65E-19 -3.4906 2.48E-60 -0.7849 1.61E-08
Pitx2 21* 66 127 -1.7112 3.08E-07 -1.8241 6.16E-11 -0.1129 0.589
Acta1 ab 412* 1463 4918 -2.1834 1.81E-197 -2.7825 0 -0.5991 9.29E-57
Tnnc2 b 115* 534 1544 -2.2744 5.62E-69 -2.9747 6.36E-204 -0.7003 4.41E-26
Atp2a1 17* 103 223 -2.6582 3.49E-17 -2.9412 1.12E-30 -0.283 0.0813
Hrc 9* 40 67 -2.2112 2.34E-06 -2.1239 1.52E-07 0.0873 0.7535
Myoz1 8* 34 58 -2.1466 1.93E-05 -2.0857 1.37E-06 0.0609 0.8391
  1. a, homologs of mouse genes, all others are the homologs of human genes; b, genes expression patterns validated by RT-qPCR; * indicates gene expression in the library is significantly higher or lower than in other two libraries (*, p < 0.001; **, p < 0.01).