IPA representation of IgE and pro-Th2 genes in network 3 from cluster 4, 24 hours post-infestation with P. ovis. Individual nodes represent protein functions with relationships represented by edges. Nodes coloured by gene expression, red indicating up-regulation and white indicating gene/factor not differentially expressed but with defined relationship to other genes in network. Arrows indicate directional relationships. Red circles highlight roles for FCER1A, FCER1G, FCGR3A, FCGR1A and selected MHC complex genes. Network score = 31.