|
Gene Symbol
|
Microarray fold change
|
qRT-PCR fold change
|
Correlation*
|
|---|
| |
1 hr
|
3 hr
|
6 hr
|
24 hrs
|
1 hr
|
3 hr
|
6 hr
|
24 hrs
| |
|---|
|
IL1B
|
4.9
|
14.6
|
5.7
|
1.7
|
41.0
|
127.4
|
52.6
|
5.2
|
0.99
|
|
IL6
|
103.3
|
771.7
|
193.0
|
15.2
|
6.4
|
11.9
|
6.1
|
1.4
|
0.92
|
|
IL8
|
44.0
|
311.9
|
231.6
|
454.6
|
21.7
|
244.5
|
293.8
|
477.4
|
0.96
|
|
TNF
|
3.4
|
1.3
|
1.5
|
1.3
|
5.2
|
2
|
2.5
|
0.8
|
0.95
|
|
IL10
|
2.2
|
2.1
|
2.8
|
2.3
|
1.8
|
1.7
|
1.9
|
0.7
|
0.4
|
|
IL18
|
1.1
|
1.1
|
1.4
|
1.3
|
1.4
|
1.3
|
1.6
|
0.7
|
0.68
|
|
TGFBI
|
1.5
|
1.3
|
1.5
|
3.2
|
1.6
|
1.7
|
1.7
|
3.2
|
0.99
|
|
TLR4
|
1.3
|
2.3
|
2.0
|
1.2
|
0.8
|
1.5
|
1.2
|
0.5
|
0.96
|
|
TLR2
|
2.0
|
4.6
|
3.4
|
2.8
|
1.5
|
2.7
|
2.3
|
1.0
|
0.83
|
|
IL4
|
4.2
|
19.5
|
28.8
|
2.2
|
1.9
|
8.7
|
9.2
|
0.8
|
0.97
|
|
CSF2
|
6.7
|
4.9
|
4.4
|
1.6
|
9.2
|
9.1
|
9.8
|
1.4
|
0.86
|
| |
Mean correlation
|
0.87
|
- Key - Comparisons between baseline samples (time = 0) and individual time points. *Correlations performed using Pearson's correlation co-efficient for highly expressed genes, i.e. IL1B, IL6, IL8, TNF, TLR4, TLR2, IL4 and CSF2 and Spearman's rank correlation co-efficient for genes with lower expression levels, i.e. IL10, IL18 and TGFBI
