Identification of small RNAs in Francisella tularensis

BMC Genomics

Table 2 Effect of ftrA and ftrB deletion on the transcriptome of LVS

Locus^a	Gene product	Fold-change in ftrA^b	Fold change in ftrB^b
FTL_0045	orotidine 5'-phosphate decarboxylase	1.8	NA
FTL_0207	pyrrolidone-carboxylate peptidase	2.6	NA
FTL_0902	oxidoreductase	1.8	NA
FTL_1922	YggT family protein	10.8	NA
FTL_0324	pseudogene	NA	0.7
FTL_0421	lipoprotein	NA	0.7
FTL_0836	hypothetical protein	NA	8.2
FTL_1754	hypothetical membrane protein	NA	1.5
FTL_1966	anthranilate synthase component I	NA	0.7

^a Genes included had ≥1.5 average fold-change in mRNA level (calculated for all spots) and for which each of the five spots for the gene on the microarray had fold-changes ≥1.2
^b Change in mRNA level in mutant strain compared to wild-type LVS

ISSN: 1471-2164