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Table 2 Selected marker and cytokine gene expression signals and their differential scores after differentiation to macrophages and DCs

From: Genome-wide promoter analysis of histone modifications in human monocyte-derived antigen presenting cells

Gene

MO

MF

DC

 

Signal

Signal

Score*

Signal

Score

CD1A

226

160

-4

7934

48

CD1B

34

794

9

11970

103

CD1C

308

105

-16

4012

39

CD4

1191

494

-26

452

-30

CD14

13904

4056

-41

122

-77

CD40

57

624

28

762

85

CCL2

19

1542

6

1022

54

CCL3

72

6355

49

3436

99

CCL13

7

462

6

21325

103

CCL17

1

65

21

19817

75

CCL22

15

7026

124

14991

103

CCL23

1

406

16

2200

18

CCL26

14

13

0

2295

26

CCR2

912

1

-26

2

-26

CSF1R

11566

3911

-26

6423

-11

LY9/SLAMF3

13

113

42

635

52

SLAMF7

63

851

58

1226

76

SLAMF8

52

2745

68

2182

98

SLAMF9

11

469

108

217

55

SELL/CD62L

2807

10

-77

7

-77

DC-SIGN/CD209

46

798

28

8191

102

DC-STAMP/TM7SF4

1

8783

125

3809

103

TREM2

1

1810

123

2834

103

  1. *Illumina BeadStudio differential expression score indicates statistical difference between expression levels. The differential score >13 corresponds to statistically significant change with P-value less than 0.05. Positive values correspond to upregulation and negative values to downregulation of expression.
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BMC Genomics

ISSN: 1471-2164

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