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Table 1 Characteristics of polyadenylation regions used for recognition of PAS-strong, PAS-weak and PAS-less sites, and Mahalonobis distance (D2; 38) showing the power of recognition of each characteristic

From: POLYAR, a new computer program for prediction of poly(A) sites in human sequences

Characteristics

D2for PAS-strong sites

D2for PAS-weak sites

D2for PAS-less sites

PAS-motif, [-40: -1]

3.18

1.98

 

CS-motif*

1.15

1.51

1.36

GU/U-motif, [+1: +50]

1.08

0.90

0.48

Upstream Pentamer Composition

0.72

0.52

0.83

Downstream Pentamer Compositionc

 

0.84

1.32

PAS-CS distance

1.24

0.77

 

CS-GT distance

0.30

0.24

0.17

Total D2:

7.67

6.75

4.16

  1. * Location of CS-motif: [-15: +3] for PAS-strong and PAS-weak sites; [-9: +3] for PAS-less sites.