Product | LaCOG | Functional domain | Distribution | Special features |
---|---|---|---|---|
Specific enzyme families | ||||
Subtilisin-like serine protease | LaCOG02153 | Subtilase family | L. casei, L. delbrueckii bulgaricus, L. johnsonii, L. lactis, S. thermophilus | PA domain (PF02225) inserted in the subtilase family domain |
 | LaCOG90024 | Subtilase family | L. acidophilus, L. casei | no PA insert domain |
Trans-glycosylase | LaCOG01094 | Transglycosylase-like domain, | mainly in L.plantarum, L.lactis, S.thermophilus | different domains for PG binding |
 | LaCOG01589 | aggregation promoting factor related surface protein | not in L.acidophilus group | PG bound by LysM domain; highly conserved C-terminal domain ending in GWY |
 | LaCOG02932 | aggregation promoting factor related surface protein | only in L.delbrueckii bulgaricus, L.plantarum, L.acidophilus group | highly conserved C-terminal domain ending in WY |
 | LaCOG90005 | aggregation promoting factor related surface protein | only in L.acidophilus group | highly conserved C-terminal domain ending in GWY |
Dextran sucrase | LaCOG90016 | glycosyl hydrolase family 70 | only in Leuconostoc, L. reuteri, O. oeni | Â |
Cell-surface hydrolases | ||||
alpha/beta hydrolase | LaCOG01137 | alpha/beta hydrolase of unknown function (DUF915) | ubiquitous | Â |
 | LaCOG01138 | alpha/beta hydrolase (DUF915) | Ubiquitous |  |
 | LacOG01920 | alpha/beta hydrolase (DUF915) | only in L. delbrueckii bulgaricus, L.plantarum , L.casei |  |
 | LaCOG02785 | alpha/beta hydrolase (DUF915) | only in L.plantarum , L.casei , L.sakei |  |
lipase/Acyl-hydrolase | LaCOG00342 | GDSL-like Lipase/Acylhydrolase | not in L.acidophilus group | with GDSL-like motif |
general cell surface hydrolase | LacOG02019 | cell surface hydrolase membrane-bound (putative) | only in L.delbrueckii bulgaricus, L.plantarum,L.casei , L.fermentum | Â |
 | LaCOG01618 | cell-surface hydrolase; | only in L.plantarum , L.delbrueckii bulgaricus, P.pentosaceus |  |
Binding proteins | ||||
mannose-specific adhesion | LaCOG01741 | MUB domain, Gram positive anchor | only in L.plantarum, L.delbrueckii bulgaricus, P.pentosaceus, L.acidophilus group | Â |
collagen-binding protein | LaCOG00092 | Collagen binding domain, Gram positive anchor | not in L.acidophilus group | Â |
mucus-binding protein | LaCOG00885 | MucBP domain (Classical), Gram positive anchor | not in L.acidophilus group | Leucine Rich Repeat, PT repeat |
 | LaCOG01470 | MUB domain, Gram positive anchor |  | many pseudogenes, most L.acidophilus group proteins have YSIRK-type signal peptide |
 | LacOG02280 | MUB domain, Gram positive anchor | only in L.acidophilus group | very large, YSIRK-type signal peptide |
 | LaCOG03211 | MUB domain, Gram positive anchor |  | 5 of 10 are pseudogenes; YSIRK SP in L.acidophilus group members |
 | LacOG99309 | MUB domain, Gram positive anchor | only in L.acidophilus group | all pseudogenes; YSIRK type signal peptide |
chitin-binding protein | LaCOG01300 | Chitin binding domain | E.faecalis, L.plantarum, L.sakei, L.lactis | maybe related to niche |
adherence protein | LaCOG01366 | von Willebrand factor type A domain, Cna protein B-type domain | only in L.lactis, E.faecalis, L.citreum, L.casei | Â |