Locus Tag | Gene Name | Identity (%) | Function | Related Pathotype |
---|---|---|---|---|
Chromosome | ||||
Adhesins | ||||
NRG857_00540 | hcpA | 89 | adherence | EHEC |
NRG857_05010 | csgE | 100 | assembly/transport component in curli production | Common |
NRG857_17655 | lpfA2 | 85 | major fimbrial subunit of Long Polar Fimbriae (Lpf), named lpfA2 | EPEC, EHEC |
NRG857_21765 | fimA | 77 | major fimbrial subunit of type 1 fimbriae | Common |
NRG857_21795 | fimH | 99 | adhesin of type 1 fimbriae | Common |
Iron acquisition/Transport systems | ||||
NRG857_06120 | fepC | 79 | ferric enterobactin transport ATP-binding protein | UPEC, EHEC |
NRG857_09890 | irp2 | 95 | yersiniabactin biosynthetic protein | UPEC |
NRG857_09895 | irp1 | 91 | yersiniabactin biosynthetic protein | UPEC |
NRG857_09915 | fyuA | 95 | pesticin/yersiniabactin receptor protein | UPEC |
NRG857_17390 | chuA | 94 | outer membrane receptor protein, heme utilization/transport protein | UPEC, EHEC |
Capsular and somatic antigens | ||||
NRG857_14650 | kpsM-II | 94 | involved in polysialic acid transport, group II (K1, K4, K5, K7, K12, K92...) | Â |
Haemolysins and haemagglutinins | ||||
NRG857_06035 | clyA | 95 | cytolysin, cell lysis | ETEC |
NRG857_01335 | tsh | 78 | temperature-sensitive hemagglutinin of avian E. coli, autotransporter | APEC |
Other | ||||
NRG857_00835 | htrA/degP | 97 | stress protein, serine endoprotease | common |
NRG857_02540 | ompT | 99 | outer membrane protein 3b, other name: protease VII | common |
NRG857_02570 | ibeB | 88 | invasion gene locus (penetration of brain microvascular endothelial cells), putative resistance protein, putative outer membrane lipoprotein of copper ion antiporter | common |
NRG857_04350 | ompA | 89 | outer membrane protein (OMPA or OMPII) | common |
NRG857_05660 | iss2 | 100 | gene for increased serum survival (similar to bacteriophage lambda Bor) | common |
NRG857_07375 | gadB | 98 | glutamate decarboxylase B, isozyme (amino acid catabolism and metabolism) | common |
NRG857_11240 | ompC | 100 | outer membrane protein | common |
NRG857_13905 | malX | 94 | maltose and glucose-specific IIABC component, pathogenicity island associated | UPEC |
NRG857_15695 | nlpI | 100 | lipoprotein | common |
NRG857_17475 | gadA | 99 | glutamate decarboxylase A, isozyme (amino acid catabolism and metabolism) | common |
NRG857_19245 | dsbA | 100 | oxidoreductase, thiol:disulfide interchange protein dsbA | common |
NRG857_21885 | ibeA | 91 | invasion protein, E. coli invasion of the blood-brain barrier, other name: ibe10 | MENEC |
Putative virulence associated genes | ||||
NRG857_00565 | usp | 93 | uropathogenic specific protein (putative virulence island of UPEC) | UPEC |
NRG857_00950 | cadA | 68 | lysine decarboxylase | common |
NRG857_03880 | artJ | 92 | L-arginine periplasmic binding protein, supposed to be involved in virulence | common |
NRG857_05150 | mviM | 93 | putative virulence factor | common |
NRG857_05155 | mviN | 86 | putative virulence factor | common |
NRG857_05410 | b1121 | 90 | hypothetical protein ycfZ, homologous to virulence factor | common |
NRG857_19995 | yjaA | 100 | hypothetical protein | common |
NRG857_20725 | cadA | 99 | Lysine decarboxylase | common |
NRG857_20730 | cadB | 100 | Lysine:cadaverine antiporter | common |
NRG857_22200 | nadAB | 99 | meningococcal adhesion, NAD biosynthesis | common |
Plasmid | ||||
Colicins and microcins | ||||
NRG857_30019 | cvaC | 83 | structural gene for microcin V | common |
NRG857_30029 | cma | 99 | structural gene for colicin M | common |
Iron acquisition/Transport systems | ||||
NRG857_30008 | iroB | 93 | siderophore | common |
NRG857_30010 | iroC | 91 | siderophore | common |
NRG857_30012 | iroD | 99 | siderophore | common |
NRG857_30013 | iroE | 93 | siderophore | common |
NRG857_30015 | iroN | 97 | siderophore | common |
NRG857_30235 | iutA | 95 | cloacin DF13/aerobactin outer membrane receptor protein | common |
NRG857_30237 | iucD | 96 | gene of the aerobactin operon, first product of the aerobactin biosynthesis pathway | common |
Other | ||||
NRG857_30184 | traT | 84 | complement resistance protein | common |
NRG857_30283 | ompT | 76 | outer membrane protein 3b, other name: protease VII | common |
NRG857_30309 | iss2 | 100 | gene for increased serum survival (similar to Bacteriophage lambda Bor) | common |
Antimicrobial resistance | ||||
NRG857_30085 | blaTEM | 94 | ampicillin | common |
NRG857_30067 | tetC | 71 | tetracycline | common |
NRG857_30068 | tetA | 91 | tetracycline | common |
NRG857_30075 | catI | 100 | chloramphenicol | common |
NRG857_30100 | dhfrI | 99 | trimethoprim | common |
NRG857_30095 | sulII | 93 | sulfonamides | common |
NRG857_30104 | sulI | 100 | sulfonamides | common |