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Table 3 Drug resistance mutations among R86 cluster isolates.

From: The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

strain Resist. sens. katG inhA rpoB embB pncA rrs ethA gyrA
R1207 IR B S315T g-17t D435V M306I +c L172 a514c, a1401g A381P D94H
X132 IRACSK EOB S315T g-17t D435V M306I +c L172 a514c, a1401g A381P wt
X28 IRACOSK EB S315T g-17t D435V M306I +c L172 a514c, a1401g A381P D94N
R1746 IR B S315T wt S450L M306I C14R a514c A381P wt
X156 IRACSK EOB S315T c-15t S450L M306I C14R a514c, a1401g A381P wt
X85 IRAOKE CB S315T c-15t S450L M306I C14R a514c, a1401g A381P D94G
  1. wt = wild-type, I = isoniazid, R = rifampicin, S = streptomycin, A = amikacin, C = capreomycin, K = kanamycin, E = ethionamide, B = ethambutol, O = ofloxacin.
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BMC Genomics

ISSN: 1471-2164

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