BMC Genomics

Table 3 Drug resistance mutations among R86 cluster isolates.

From: The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

strain	Resist.	sens.	katG	inhA	rpoB	embB	pncA	rrs	ethA	gyrA
R1207	IR	B	S315T	g-17t	D435V	M306I	+c L172	a514c, a1401g	A381P	D94H
X132	IRACSK	EOB	S315T	g-17t	D435V	M306I	+c L172	a514c, a1401g	A381P	wt
X28	IRACOSK	EB	S315T	g-17t	D435V	M306I	+c L172	a514c, a1401g	A381P	D94N
R1746	IR	B	S315T	wt	S450L	M306I	C14R	a514c	A381P	wt
X156	IRACSK	EOB	S315T	c-15t	S450L	M306I	C14R	a514c, a1401g	A381P	wt
X85	IRAOKE	CB	S315T	c-15t	S450L	M306I	C14R	a514c, a1401g	A381P	D94G

wt = wild-type, I = isoniazid, R = rifampicin, S = streptomycin, A = amikacin, C = capreomycin, K = kanamycin, E = ethionamide, B = ethambutol, O = ofloxacin.

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ISSN: 1471-2164

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