BMC Genomics

Table 4 Drug resistance mutations among R220 cluster isolates.

From: The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

strain	resist.	sens.	katG	inhA	rpoB	embB	pncA	rrs	rpsL	gyrA
R1909	IRB		wt	c-15t, I194T	S450L	M306V	D8N	a1401g	wt	wt
R1842	I	RB	wt	c-15t	S450L	M306V	wt	c517t	wt	D94A
X122	IRO	EAB	wt	c-15t	S450L	M306I	Y103*	wt	K43R	D94G
R1390	I		wt	c-15t	wt	wt	wt	wt	wt	wt
X189	IRACOK	ES	wt	c-15t, I194T	S450L	M306V	881 bp del	a1401g	wt	D94A
R1505	IR	B	wt	c-15t	H445Y	wt	wt	wt	wt	wt
R1441	I	RB	wt	c-15t	wt	M306I	wt	wt	wt	wt
X29	IRASK	BOCE	wt	c-15t	wt	M306V	8 bp del	a1401g	wt	wt

wt = wild-type, I = isoniazid, R = rifampicin, S = streptomycin, A = amikacin, C = capreomycin, K = kanamycin, E = ethionamide, B = ethambutol, O = ofloxacin.

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ISSN: 1471-2164

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