| consensus class 1 | consensus class 2 | consensus class 3 | total consensus | total non consensus | |
---|
AD-wrmcDNA library | 20% | 24% | 5% | 49% | 51% | n = 447 |
AD-ORFeome library | 10% | 18% | 5% | 33% | 66% | n = 227 |
C. elegans proteome | 8% | 18% | 5% | 31% | 69% | n = 20186 |
| consensus class 1
| consensus class 2
| consensus class 3
| total consensus
| total non consensus
| |
AD-wrmcDNA library | 18% | 21% | 5% | 44% | 56% | n = 317 nr |
AD-ORFeome library | 9% | 15% | 4% | 28% | 72% | n = 178 nr |
C. elegans proteome | 8% | 18% | 5% | 31% | 69% | n = 20186 |
- Proportions of C-terminal consensus classes for interacting proteins identified in AD-wrmcDNA and AD-ORFeome screens compared with proportions of C-terminal consensus classes in the complete C. elegans proteome (WS190 [16]) are given. Consensus class 1: [ST]X[FWCYMVILA], Consensus class 2 [YFWCMVILA]X[YFWCMVILA], Consensus class 3 [DE]X[YFWCMVILA] (X: any amino acid). Upper panel: proportions calculated using all PDZ-interacting protein pairs, lower panel: proportions calculated using each interacting protein only once when interacting with multiple PDZ domains (nr stands for non-redundant).