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Table 5 Highly conserved residues shared by 66 cluster-associated (including those from the 49 novel clusters referred to in this paper) lanthionine dehydratases (LanB).

From: In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria

From Alignment

NisB Position

% Conservation

Motifs

  

YxxR

80-83

89%

RxTPFG

87-94

77%

FxxxYG

342-347

82%

GxG

363-365

92%

GRF

463-465

86%

PxxxRxxNV

501-509

50%

RFL

585-587

51%

RYG

826-828

85%

HxxxNR

961-966

70%

Single Residues

  

R

14

86%

D

121; 299; 648; 843

86%; 94%; 94%; 85%

N

145

86%

L

217

97%

P

612; 639

100%; 95%

E

975

89%

W

616

98%

F

840

95%

V

352

83%

  1. Residues are numbered according to their position in NisB