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Table 6 Highly conserved residues shared by 66 cluster-associated (including those from 49 novel clusters) lanthionine cyclases. Residues are numbered according to their position in NisC

From: In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria

Conserved Residues

NisC Position

% Conservation

Motifs

  

LxxG

39-42

83%

YDxxxGxxG

140-148

67%

GxAHGxxG

209-216

83%

WCYG

283-286

95%

CHG

330-332

98%

GxxxGxxGxxLxL

377-389

73%

Single Residues

  

G

90

94%

W

258; 401

83%; 92%