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Table 6 Highly conserved residues shared by 66 cluster-associated (including those from 49 novel clusters) lanthionine cyclases. Residues are numbered according to their position in NisC

From: In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria

Conserved Residues NisC Position % Conservation
Motifs   
LxxG 39-42 83%
YDxxxGxxG 140-148 67%
GxAHGxxG 209-216 83%
WCYG 283-286 95%
CHG 330-332 98%
GxxxGxxGxxLxL 377-389 73%
Single Residues   
G 90 94%
W 258; 401 83%; 92%