A. succinogenes central metabolic network based on annotation of metabolic genes. Four-digit numbers are Asuc_ORF (locus tags) numbers and are followed by E.C. numbers. Hyphenated locus tag numbers indicate that the enzyme is encoded by several successive genes. Reaction names: see additional file 2: Table S3. Arrow and number colors: black, product function assumed; green, putative function assumed; blue, probable function assumed; red, possible function assumed. Metabolites: AcCoA, acetyl-CoA; Ace, acetate; AcP, acetyl-phosphate; Ald, acetaldehyde; Cit, citrate; EtOH, ethanol; E4P, erythrose-4-phosphate; For, formate; Fum, fumarate; F1,6P, fructose-1,6-bisphosphate; F6P, fructose-6-phosphate; Glc, glucose; G1,3P, glycerate-1,3-bisphosphate; G3P, glyceraldehyde-3-phosphate; G6P, glucose-6-phosphate; Icit, Isocitrate; αKG, α-ketoglutarate; Mal, malate; OAA, oxaloacetate; PEP, phosphoenolpyruvate; 2PG, 2-phosphoglycerate; 3PG, 3-phosphoglycerate; Pyr, pyruvate; Q+, menaquinone; QOH, menaquinol; R5P, ribose-5-phosphate, Ru5P, ribulose-5-phosphate, Suc, succinate; SucCoA, succinyl-CoA; S7P, sedoheptulose-7-phosphate; X5P, xylulose-5-phosphate.