Figure 2

Cumulative size and composition of the Listeria pan-genome. (a) Cumulative pan-genome size plots were calculated by selecting strains without replacement in random order 500 times, and then calculating the mean pan-genome size at each sampling point (solid red line). Error bars indicate one standard deviation from the mean. Estimated pan-genome size from mixture model analysis is indicated as a dotted cyan line. (b) The graphical display of the mixture model represents the four components of the pan-genome as rectangles, including (i) a component of 31% of the genes with a detection probability of 1.0 (blue: the core-genome), (ii) a component representing 7% of the genes with a detection probability of 0.82 (teal), (iii) a component of 10% of the genes with a detection probability of 0.33 (yellow), and (iv) a component of 52% of the genes with a detection probability of 0.06 (rare genes: orange).