Comparative genomics of the bacterial genus Listeria: Genome evolution is characterized by limited gene acquisition and limited gene loss

Table 4 Variable virulence associated genes other than those found in the prfA cluster and their distribution in the genomesa

Gene designation	EGD-e homologue	Lm^bEGD-e	Lm^bF2365	Lm^bCLIP 80459	Lm^blineage IIIA	Lm^blineage IIIC	Li^bhly+	Liv^b	Ls^bhly+	Ls^bhly-	Lma^bhly-	Li^bhly-1	Li^bhly-2	Lw^bhly-
lmo0206	lmo0206	+	+	+	+	+	+	-	-	-	-	-	-	-
lmo0257	lmo0257	+	+	+	+	+	+	+	+	+	+	-	-	+
inlH/inlC2	lmo0263	+	+	+	-	+	-	-	-	-	-	-	-	-
vip	lmo0320	+	+	+	-	-	-	-	-	-	-	-	-	-
inlA ^a	lmo0433	+	+	+	+	+	+	+	-	-	-	-	-	-
inlB ^a	lmo0434	+	+	+	+	+	-	+	-	-	-	-	-	-
uhpT	lmo0838	+	+	+	+	+	+	+	+	+	-	-	-	-
lmo0915	lmo0915	+	+	+	+	+	+	+	-	+	+	+	+	+
aut	lmo1076	+	+	+	+	-	+	+	+	+	+	+	+	+
lmo1081	lmo1081	+	-	-	-	-	-	-	+	-	-	-	-	-
lmo1082	lmo1082	+	-	-	-	-	-	-	+	-	-	-	-	-
lmo1099	lmo1099	+	-	-	-	-	-	-	-	-	-	-	-	-
lmo1102	lmo1102	+	-	-	-	-	-	-	-	-	-	-	-	-
lmo1290	lmo1290	+	+	+	+	+	-	+	-	+	+	-	-	-
inlC ^a	lmo1786	+	+	+	-	+	-	+	-	-	-	-	-	-
lmo2026	lmo2026	+	-	-	-	-	-	-	-	-	-	-	-	-
bsh	lmo2067	+	+	+	+	+	-	-	-	-	-	-	-	-
lmo2157	lmo2157	+	+	+	-	-	-	+	-	-	+	-	-	-
lmo2439	lmo2439	+	+	+	+	+	+	+	+	-	+	+	+	+
ami	lmo2558	+	+	+	+	+	-	-	+	+	+	+	+	+
lmo2713	lmo2713	+	+	+	+	+	+	-	+	+	+	+	+	+
inlJ	lmo2821	+	+	+	-	+	-	-	-	-	-	-	-	-

^a The genes listed here are based on 78 putative virulence associated genes reported by Camejo et al. [45]. Only 22 genes found to show variable presence among the 13 genomes analyzed here are shown. The absence of the prfA-cluster, inlA, inlB and inlC was additionally confirmed by PCR and in some cases sequencing (see additional file 1 for more information).
^b Lm = L. monocytogenes; Li hly-1 = L. innocua CLIP 11262 (hemolysis negative); Li hly-2 = L. innocua FSL S4-378 (hemolysis negative); Li hly+ = L. innocua FSL J1-023 (hemolysis positive); Lma = L. marthii FSL S4-120; Lw = L. welshimeri SLCC5334; Liv = L. ivanovii subsp. londoniensis ATCC 49954; Ls hly+= L. seeligeri FSL N1-067 (hemolysis positive); Ls hly-= L. seeligeri FSL S4-171 (hemolysis negative).

ISSN: 1471-2164