Table 2 Genes down-regulated in A. pleuropneumoniae under iron limitation

APL_1757⁺

fumC

fumarate hydratase

C

-0.83

APL_1675

dms B

anaerobic dimethyl sulfoxide reductase chain B

C

-2.00

APL_1674⁺

dmsA

Anaerobic dimethyl sulfoxide reductase chain A precursor

C

-2.07

APL_1572

-

Predicted membrane protein

S

-0.67

APL_1546

hcp

hydroxylamine reductase, catalyzes the reduction of hydroxylamine to ammonia and water (Fe-S cluster containing protein)

C

-1.28

APL_1529⁺

frdA

Fumarate reductase flavoprotein subunit

C

-0.90

APL_1528⁺

frdB

Fumarate reductase iron-sulfur subunit

C

-0.90

APL_1527⁺

frdC

Fumarate reductase subunit C

C

-1.39

APL_1526

frdD

Fumarate reductase subunit D

C

-1.37

APL_1496

Predicted esterase

R

-0.24

APL_1432

-

Putative NAD(P)H oxidoreductase

R

-0.66

APL_1431⁺

napF

Ferredoxin-type protein

C

-1.23

APL_1430

napD

putative periplasmic nitrate reductase protein

P

-1.66

APL_1429

napA

Periplasmic nitrate reductase

C

-1.14

APL_1428

napG

Quinol dehydrogenase periplasmic component

C

-1.39

APL_1427

napH

Quinol dehydrogenase membrane component

C

-1.14

APL_1426

napB

Nitrate reductase cytochrome c-type subunit

C

-1.60

APL_1422

napC

Nitrate/TMAO reductase

C

-1.42

APL_1379

mauG ^#

Cytochrome c peroxidase

P

-1.95

APL_1367⁺

ccmF

Cytochrome c-type biogenesis protein

O

-0.54

APL_1337

hypG

Hydrogenase maturation factor

O

-0.68

APL_1336

hybE

Hydrogenase 2-specific chaperone

S

-1.00

APL_1335

hyaD

Ni, Fe-hydrogenase maturation factor

C

-0.99

APL_1334

hyaB

Ni, Fe-hydrogenase I large subunit

C

-1.06

APL_1333

hybB

Putative cytochrome b subunit of the hydrogenase 2

C

-1.17

APL_1332

hybA2

Fe-S-cluster-containing hydrogenase components 1

C

-1.95

APL_1331⁺

hyaA ^#

Ni, Fe-hydrogenase I small subunit

C

-2,51

APL_1328

hybD ^#

Hydrogenase maturation factor

O

-1.90

APL_1327

hypB ^#

Hydrogenase nickel incorporation protein

OK

-2.1

APL_1316⁺

dcuB2

Anaerobic C4-dicarboxylate membrane transporter

R

-0.78

APL_1253

-

Di- and tricarboxylate transporter

P

-0.83

APL_1216

luxS

S-ribosylhomocysteine lyase

T

-0.39

APL_1213

-

Predicted phosphatase/phosphohexomutase

R

-1.21

APL_1237

-

Possible integral membrane sulfate transporter

P

-0.64

APL_1162

-

Predicted iron-dependent peroxidase

P

-0.41

APL_1156

citT

Di-and tricarboxylate transporter

P

-1.20

APL_1129

cytB562

Soluble cytochrome b562

C

-0.48

APL_1124⁺

pfkA

6-phosphofructokinase

G

-0.37

APL_1086⁺

ompW

OM protein ompW precursor

M

-1.53

APL_1036⁺

pflB

Formate acetyltransferase

C

-0.38

APL_1011⁺

adh2

Alcohol dehydrogenase, class IV/NAD-dependent aldehyde dehydrogenases

C

-1.24

APL_0966

-

Putative transport protein

R

-0.71

APL_0895

fdnI

Formate dehydrogenase, gamma subunit

C

-1.15

APL_0894⁺

fdxH

Formate dehydrogenase, iron-sulfur subunit

C

-1.17

APL_0893⁺

fdxG

Formate dehydrogenase, nitrate-inducible, major subunit

C

-1.01

APL_0892

fdxG

Formate dehydrogenase, nitrate-inducible, major subunit

C

-1.18

APL_0857

sdaA ^#

L-serine dehydratase (gluconeogenesis)

E

-1.00

APL_0856

sdaC ^#

serine transporter

E

-1.58

APL_0780

lrgA2 ^#

Putative effector of murein hydrolase LrgA

R

-1.11

APL_0779

-

Putative effector of murein hydrolase

M

-0.90

APL_0723

tgt

Queuine tRNA-ribosyltransferase

J

-0.15

APL_0689⁺

torY

Cytochrome c-type protein

C

-2.30

APL_0688⁺

torZ

Trimethylamine-N-oxide reductase precursor

C

-1.61

APL_0607⁺

nfnB

Putative NAD(P)H nitroreductase

C

-0.54

APL_0446⁺

ykgE

Putative dehydrogenase subunit, Fe-S oxidoreductase

C

-2.63

APL_0445⁺

ykgF

Iron-sulfur electron transport protein

C

-1.79

APL_0444⁺

engA

Putative GTP binding protein

S

-1.10

APL_0416

-

N-acetyl-D-glucosamine kinase

KG

-0.36

APL_0155⁺

nqrF

Na+-translocating NADH-ubiquinone oxidoreductase subunit F

C

-0.37

APL_0154⁺

nqrE

Na+-transporting NADH-ubiquinone oxidoreductase subunit E

C

-0.35

APL_0153⁺

nqrD

Na+-translocating NADH-ubiquinone oxidoreductase subunit D

C

-0.47

APL_0152⁺

nqrC

Na+-translocating NADH-ubiquinone oxidoreductase subunit C

C

-0.33

APL_0151⁺

nqrB

Na+-translocating NADH-ubiquinone oxidoreductase subunit B

C

-0.40

APL_0150⁺

nqrA

Na+-translocating NADH-ubiquinone oxidoreductase subunit A

C

-0.46

APL_0103

nrfD ^#

Nitrate reductase, transmembrane protein

P

-1.51

APL_0101⁺

nrfB ^#

Cytochrome c nitrite reductase pentaheme subunit

C

-2.17

APL_0100⁺

nrfA ^#

Nitrate reductase, cytochrome c552, catalyzes the formate-dependent reduction of nitrite to ammonia;

P

-2.34