Clusters of secondary metabolite processing genes identified in the P. vortex genome. Non-ribosomal polyketide synthetase/polyketide synthetase is marked red; transporter genes marked blue; accessory genes marked green; hypothetical genes marked yellow. (A) Putative polyketide synthase gene cluster. (B) Non-ribosomal peptide synthetase gene cluster potentially involved in bacillibactin-like siderophore synthesis. (C) A hybrid gene cluster of polyketide synthase and nonribosomal peptide synthetase involved in bacitracine-like antibiotic synthesis.