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Figure 2 | BMC Genomics

Figure 2

From: Combining modularity, conservation, and interactions of proteins significantly increases precision and coverage of protein function prediction

Figure 2

Illustration of the detection of CCS. Protein interaction networks are compared across different species to identify evolutionary and conserved subgraphs. First, orthology relationships across multiple species are determined by using OrthoMCL. Second, all pairs of conserved interactions (interologs) are identified between the orthologs within the species. Adjacent interologs are then assembled to CCS.

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