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Table 1 Summary of Analysis Results

From: Accounting for multiple comparisons in a genome-wide association study (GWAS)

Method

Significance Threshold

Corresponding α level

Bonferroni

0.71 × 10-7

0.046

PRESTO

0.76 × 10-7

0.05

simpleℳ

0.82 × 10-7

0.053

SLIDE

1.09 × 10-7

0.068

Gabriel

2.72 × 10-7

0.151

4-Gamete

3.06 × 10-7

0.166

Solid spine

3.71 × 10-7

0.195

  1. The significance threshold for each method is shown (αGWAS = 0.05), as well as the corresponding genome-wide α level when compared with the PRESTO method. A strict Bonferroni significance threshold is also given.
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BMC Genomics

ISSN: 1471-2164

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