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Table 2 Difference in Significance Threshold in a Subset of the Data

From: Accounting for multiple comparisons in a genome-wide association study (GWAS)

Method

Δ Significance Threshold

simple

-8 × 10-11

4-Gamete

-8 × 10-10

SLIDE

-5 × 10-9

Gabriel

-6 × 10-8

PRESTO

7 × 10-7

Solid spine

-8 × 10-7

  1. The difference in significance threshold is given, comparing an analysis of the full data set to a subset of the data with an equal number of cases and controls (1,514 and 518 individuals, respectively).