Table 3 Comparison of α levels when restricting the definition of a haplotype
From: Accounting for multiple comparisons in a genome-wide association study (GWAS)
Method | Parameters | Significance Threshold | Corresponding α level |
|---|---|---|---|
Gabriel | D'U > 0.98 | 2.72 × 10-7 | 0.151 |
D'L > 0.70 | |||
D'U > 0.98 | 2.11 × 10-7 | 0.12 | |
D'L > 0.85 | |||
4-Gamete | Cutoff = 1% | 3.06 × 10-7 | 0.166 |
Cutoff = 0.5% | 2.50 × 10-7 | 0.139 | |
Solid spine | D' = 0.80 | 3.71 × 10-7 | 0.195 |
D' = 0.95 | 2.79 × 10-7 | 0.155 |