Skip to main content

Table 1 Probes overexpressed in XX versus XO mice in each tissue

From: Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome

  

Liver

Kidney

Muscle

Brain

   

FC

 

FC

 

FC

 

FC

Probe ID

Gene

P-value

Array

qPCR

P-value

Array

qPCR

P-value

Array

qPCR

P-value

Array

qPCR

2649129

Eif2s3x

6,17E-07

1,79

1,54±0,21

1,81E-03

1,48

1,43±0,02

1,11E-02

1,35

1,83±0,26

>0,05

1,38

1,79±0,33

2447456

Utx

4,79E-05

1,34

1,97±0,35 a

2,16E-03

1,37

1,88±0,15 c

1,53E-03

1,60

2,04±0,24 d

>0,05

1,12

1,38±0,14 e

2506528

Utx

4,96E-05

1,62

1,97±0,35 a

1,98E-04

1,51

1,88±0,15 c

4,83E-03

1,46

2,04±0,24 d

>0,05

1,17

1,38±0,14 e

2508945

Lamp2

1,69E-04

1,29

1,04±0,10

>0,05

1,03

-

>0,05

1,02

-

>0,05

1,08

-

2700885

Rgn

8,07E-04

1,38

-

ND

ND

ND

ND

ND

ND

ND

ND

ND

2710166

Ddx3x

9,17E-04

1,49

1,44±0,25

>0,05

1,27

1,08±0,10

>0,05

1,09

1,33±0,10

>0,05

1,08

1,56±0,24

1235933

Utx

2,25E-03

1,18

1,97±0,35 a

3,35E-03

1,18

1,88±0,15 c

>0,05

1,13

2,04±0,24 d

>0,05

1,04

1,38±0,14 e

1231201

Pja1

2,30E-03

1,22

1,24±0,26

>0,05

1,08

1,33±0,08

>0,05

1

-

>0,05

0,98

-

2473374

Zdhhc9

2,47E-03

1,18

-

>0,05

1,01

-

>0,05

0,94

-

>0,05

1,02

-

1249467

Rap2c

3,13E-03

1,45

-

>0,05

1,18

-

>0,05

0,89

-

>0,05

1,06

-

1220409

Cetn2

3,18E-03

1,17

-

ND

ND

ND

>0,05

0,88

-

>0,05

1,05

 

2605212

Slc6a8

3,27E-03

1,25

-

>0,05

0,95

-

>0,05

0,97

-

>0,05

0,97

-

2494747

Huwe1

3,51E-03

1,31

-

>0,05

1,11

-

>0,05

0,96

-

>0,05

0,93

-

2540573

LOC665281

4,61E-03

1,34

-

>0,05

1,05

-

>0,05

0,93

-

>0,05

0,97

-

1247078

Ogt

7,74E-03

1,11

1,12±0,14b

>0,05

1,05

-

>0,05

0,94

-

>0,05

0,95

-

1236901

Maob

8,04E-03

1,17

1,04±0,06

>0,05

1,02

-

>0,05

0,97

-

>0,05

1

-

1225930

LOC100039346

8,16E-03

1,28

-

>0,05

1,06

-

>0,05

0,86

-

>0,05

0,88

-

1253604

Jarid1c

8,93E-03

1,12

1,53±0,06

>0,05

1,13

1,32±0,19

>0,05

1,12

1,43±0,01

>0,05

1,06

1,16±0,14

2740445

Nsbp1

9,76E-03

1,31

0,97±0,02

>0,05

0,98

-

>0,05

0,85

-

>0,05

1,06

-

1251370

Ndufa1

9,78E-03

1,15

1,13±0,30

>0,05

0,84

-

>0,05

0,83

-

>0,05

1,02

-

2694999

2610029G23Rik

9,88E-03

1,19

1,24±0,12

2,53E-03

1,26

1,45±0,24

4,88E-04

1,44

1,27±0,14

>0,05

1,27

1,21±0,10

2639642

Arhgef6

9,90E-03

1,12

-

>0,05

1,04

-

>0,05

1,03

-

>0,05

0,81

-

2751935

Sytl4

1,19E-02

1,13

-

>0,05

1,09

-

>0,05

1

-

>0,05

0,93

-

2623216

Pgrmc1

1,29E-02

1,41

1±0,21

>0,05

1,11

-

>0,05

0,83

-

>0,05

0,87

-

2651886

Pgk1

2,32E-02

1,19

-

>0,05

1,01

-

>0,05

0,96

-

>0,05

1,02

-

2590998

Acsl4

2,38E-02

1,21

-

>0,05

0,95

-

>0,05

1

-

>0,05

0,98

-

1236524

Msn

2,77E-02

1,15

-

>0,05

0,93

-

>0,05

1

-

>0,05

0,98

-

2611676

Ogt

2,82E-02

1,16

1,12±0,14b

>0,05

1,1

-

>0,05

0,98

-

>0,05

0,85

-

2637249

Bgn

2,85E-02

1,14

-

>0,05

0,95

-

>0,05

0,94

-

>0,05

0,99

-

1212894

Cask

3,09E-02

1,15

-

>0,05

1,03

-

>0,05

0,98

-

>0,05

0,99

-

2501489

Was

3,19E-02

1,10

-

>0,05

1,05

-

>0,05

0,97

-

>0,05

1

-

1220398

Armcx2

3,20E-02

1,17

-

>0,05

1,09

-

>0,05

1,04

-

>0,05

0,97

-

1229474

Gm732

4,42E-02

1,10

-

>0,05

1,02

-

>0,05

0,99

-

>0,05

0,95

-

2423331

Rbmx

4,54E-02

1,09

-

>0,05

0,99

-

>0,05

1

-

>0,05

0,98

-

1246006

Armcx4

>0,05

0,98

-

>0,05

0,98

-

1,84E-02

1,30

-

>0,05

1,05

-

1244364

Pnck

ND

ND

ND

ND

ND

ND

1,88E-02

1,15

1,22 ± 0,27

>0,05

0,76

-

  1. Indicated are the probes (Illumina ID) which were significantly different in each tissue in the pairwise comparison of XX and XO mice, where only the X chromosome probes were considered. P-values were derived from limma followed by FDR correction. For selected genes, fold changes obtained by qPCR (mean of two experiments ± standard error) are also indicated (a,b,c,d,e - each of these values refers to a measurement using one pair of primers). In bold are the genes for which significant p-values were obtained by both methods in at least one tissue. Xist was not included but was significant in all comparisons. ND, not detected; qPCR, quantitative real-time PCR; FC, fold-change.
Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us