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Table 1 Probes overexpressed in XX versus XO mice in each tissue

From: Transcriptional changes in response to X chromosome dosage in the mouse: implications for X inactivation and the molecular basis of Turner Syndrome

   Liver Kidney Muscle Brain
    FC   FC   FC   FC
Probe ID Gene P-value Array qPCR P-value Array qPCR P-value Array qPCR P-value Array qPCR
2649129 Eif2s3x 6,17E-07 1,79 1,54±0,21 1,81E-03 1,48 1,43±0,02 1,11E-02 1,35 1,83±0,26 >0,05 1,38 1,79±0,33
2447456 Utx 4,79E-05 1,34 1,97±0,35 a 2,16E-03 1,37 1,88±0,15 c 1,53E-03 1,60 2,04±0,24 d >0,05 1,12 1,38±0,14 e
2506528 Utx 4,96E-05 1,62 1,97±0,35 a 1,98E-04 1,51 1,88±0,15 c 4,83E-03 1,46 2,04±0,24 d >0,05 1,17 1,38±0,14 e
2508945 Lamp2 1,69E-04 1,29 1,04±0,10 >0,05 1,03 - >0,05 1,02 - >0,05 1,08 -
2700885 Rgn 8,07E-04 1,38 - ND ND ND ND ND ND ND ND ND
2710166 Ddx3x 9,17E-04 1,49 1,44±0,25 >0,05 1,27 1,08±0,10 >0,05 1,09 1,33±0,10 >0,05 1,08 1,56±0,24
1235933 Utx 2,25E-03 1,18 1,97±0,35 a 3,35E-03 1,18 1,88±0,15 c >0,05 1,13 2,04±0,24 d >0,05 1,04 1,38±0,14 e
1231201 Pja1 2,30E-03 1,22 1,24±0,26 >0,05 1,08 1,33±0,08 >0,05 1 - >0,05 0,98 -
2473374 Zdhhc9 2,47E-03 1,18 - >0,05 1,01 - >0,05 0,94 - >0,05 1,02 -
1249467 Rap2c 3,13E-03 1,45 - >0,05 1,18 - >0,05 0,89 - >0,05 1,06 -
1220409 Cetn2 3,18E-03 1,17 - ND ND ND >0,05 0,88 - >0,05 1,05  
2605212 Slc6a8 3,27E-03 1,25 - >0,05 0,95 - >0,05 0,97 - >0,05 0,97 -
2494747 Huwe1 3,51E-03 1,31 - >0,05 1,11 - >0,05 0,96 - >0,05 0,93 -
2540573 LOC665281 4,61E-03 1,34 - >0,05 1,05 - >0,05 0,93 - >0,05 0,97 -
1247078 Ogt 7,74E-03 1,11 1,12±0,14b >0,05 1,05 - >0,05 0,94 - >0,05 0,95 -
1236901 Maob 8,04E-03 1,17 1,04±0,06 >0,05 1,02 - >0,05 0,97 - >0,05 1 -
1225930 LOC100039346 8,16E-03 1,28 - >0,05 1,06 - >0,05 0,86 - >0,05 0,88 -
1253604 Jarid1c 8,93E-03 1,12 1,53±0,06 >0,05 1,13 1,32±0,19 >0,05 1,12 1,43±0,01 >0,05 1,06 1,16±0,14
2740445 Nsbp1 9,76E-03 1,31 0,97±0,02 >0,05 0,98 - >0,05 0,85 - >0,05 1,06 -
1251370 Ndufa1 9,78E-03 1,15 1,13±0,30 >0,05 0,84 - >0,05 0,83 - >0,05 1,02 -
2694999 2610029G23Rik 9,88E-03 1,19 1,24±0,12 2,53E-03 1,26 1,45±0,24 4,88E-04 1,44 1,27±0,14 >0,05 1,27 1,21±0,10
2639642 Arhgef6 9,90E-03 1,12 - >0,05 1,04 - >0,05 1,03 - >0,05 0,81 -
2751935 Sytl4 1,19E-02 1,13 - >0,05 1,09 - >0,05 1 - >0,05 0,93 -
2623216 Pgrmc1 1,29E-02 1,41 1±0,21 >0,05 1,11 - >0,05 0,83 - >0,05 0,87 -
2651886 Pgk1 2,32E-02 1,19 - >0,05 1,01 - >0,05 0,96 - >0,05 1,02 -
2590998 Acsl4 2,38E-02 1,21 - >0,05 0,95 - >0,05 1 - >0,05 0,98 -
1236524 Msn 2,77E-02 1,15 - >0,05 0,93 - >0,05 1 - >0,05 0,98 -
2611676 Ogt 2,82E-02 1,16 1,12±0,14b >0,05 1,1 - >0,05 0,98 - >0,05 0,85 -
2637249 Bgn 2,85E-02 1,14 - >0,05 0,95 - >0,05 0,94 - >0,05 0,99 -
1212894 Cask 3,09E-02 1,15 - >0,05 1,03 - >0,05 0,98 - >0,05 0,99 -
2501489 Was 3,19E-02 1,10 - >0,05 1,05 - >0,05 0,97 - >0,05 1 -
1220398 Armcx2 3,20E-02 1,17 - >0,05 1,09 - >0,05 1,04 - >0,05 0,97 -
1229474 Gm732 4,42E-02 1,10 - >0,05 1,02 - >0,05 0,99 - >0,05 0,95 -
2423331 Rbmx 4,54E-02 1,09 - >0,05 0,99 - >0,05 1 - >0,05 0,98 -
1246006 Armcx4 >0,05 0,98 - >0,05 0,98 - 1,84E-02 1,30 - >0,05 1,05 -
1244364 Pnck ND ND ND ND ND ND 1,88E-02 1,15 1,22 ± 0,27 >0,05 0,76 -
  1. Indicated are the probes (Illumina ID) which were significantly different in each tissue in the pairwise comparison of XX and XO mice, where only the X chromosome probes were considered. P-values were derived from limma followed by FDR correction. For selected genes, fold changes obtained by qPCR (mean of two experiments ± standard error) are also indicated (a,b,c,d,e - each of these values refers to a measurement using one pair of primers). In bold are the genes for which significant p-values were obtained by both methods in at least one tissue. Xist was not included but was significant in all comparisons. ND, not detected; qPCR, quantitative real-time PCR; FC, fold-change.