Table 1 Gene ontologies revealed by BiNGO for ranked positional candidates
From: Gene prioritization in Type 2 Diabetes using domain interactions and network analysis
GO ID | Gene ontology - description | No. of ranked candidates | p-value |
|---|---|---|---|
GO:0008151 | Cellular process | 279 | 1.3 × 10-3 |
GO:0008152 | Metabolic process | 237 | 1.8 × 10-12 |
GO:0044237 | Primary metabolic process | 225 | 3.6 × 10-13 |
GO:0044238 | Cellular metabolic process | 250 | 1.5 × 10-13 |
GO:0043170 | Macromolecule metabolic process | 198 | 1.7 × 10-10 |
GO:0019358 | Protein metabolic process | 160 | 1.2 × 10-28 |
GO:0044260 | Cellular macromolecule metabolic process | 159 | 2.0 × 10-30 |
GO:0044267 | Cellular protein metabolic process | 158 | 1.3 × 10-30 |
GO:0043283 | Biopolymer metabolic process | 144 | 4.1 × 10-5 |
GO:0065007 | Biological regulation | 138 | 4.3 × 10-3 |
GO:0050791 | Regulation of biological process | 118 | 0.018 |
GO:0051244 | Regulation of cellular process | 108 | 0.04 |
GO:0007154 | Cell communication | 106 | 0.026 |
GO:0006464 | Protein modification process | 100 | 4.9 × 10-22 |
GO:0043412 | Biopolymer modification | 100 | 5.4 × 10-21 |
GO:0007165 | Signal transduction | 97 | 0.036 |
GO:0043687 | Post-translational protein modification | 96 | 2.1 × 10-25 |
GO:0006796 | Phosphate metabolic process | 85 | 2.0 × 10-30 |
GO:0006793 | Phosphorus metabolic process | 85 | 5.0 × 10-30 |
GO:0016310 | Phosphorylation | 84 | 5.3 × 10-36 |
GO:0006468 | Protein amino acid phosphorylation | 83 | 2.3 × 10-41 |
GO:0051869 | Response to stimulus | 77 | 4.5 × 10-3 |
GO:0007242 | Intracellular signaling cascade | 55 | 2.2 × 10-4 |
GO:0006950 | Response to stress | 50 | 1.5 × 10-7 |
GO:0051242 | Positive regulation of cellular process | 38 | 7.5 × 10-4 |
GO:0002376 | Immune system process | 31 | 0.011 |
GO:0007243 | Protein kinase cascade | 27 | 0.017 |
GO:0006629 | Lipid metabolic process | 20 | 0.027 |
GO:0012501 | Programmed cell death | 27 | 0.034 |
GO:0006954 | Inflammatory response | 23 | 3.4 × 10-6 |