Skip to main content
Figure 3 | BMC Genomics

Figure 3

From: Systematic overrepresentation of DNA termini and underrepresentation of subterminal regions among sequencing templates prepared from hydrodynamically sheared linear DNA molecules

Figure 3

Distribution of DNA breaks in the regions flanking the Swa I cut site. The positions of breaks were determined by mapping the starts of sequence reads back to the cosmid assembly. Only reads that started with a visible pBC polylinker sequence were included. Shown are the results of a sliding window analysis of break distribution in the circular and linear DNA samples sheared to an average size of 3.8 kb. Window size was 1 kb and step size was 100 bp. The scale at the bottom represents the distance from the nearest window edge to the Swa I site.

Back to article page

BMC Genomics

ISSN: 1471-2164

Contact us