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Table 3 Clusters of adjacent genes that show similar changes in expression when B. cenocepacia J2315 biofilms are exposed to H2O2 or NaOCl.

From: Transcriptional response of Burkholderia cenocepacia J2315 sessile cells to treatments with high doses of hydrogen peroxide and sodium hypochlorite

  

Fold change in expression in treated biofilms vs untreated biofilms

Gene number

Annotation

H2O2(30 min)

NaOCl (5 min)

BCAL1763

Putative exported protein

15.5

30.2

BCAL1764

Putative exported protein

5.3

15.3

BCAL1765

Putative exported protein

7.5

31.0

BCAL1766

OsmC-like protein (Ohr protein, see text)

18.0

75.2

BCAS0084

TetR family regulatory protein

5.9

3.8

BCAS0085

Organic hydroperoxide resistance protein

49.3

20.3

BCAS0086

Putative exported lipase

96.6

11.3

BCAM0930

Putative ankyrin-like protein (ankB)

2.7

NS

BCAM0931

Catalase precursor

5.7

NS

BCAM1216

Alkyl hydroperoxide reductase F subunit (ahpF)

15.5

2.1

BCAM1217

Alkyl hydroperoxide reductase C subunit (ahpC)

41.3

15.0

BCAL1688

Putative RNA polymerase σ 70 factor (orbS)

6.4

NS

IG1_1847123

IG between BCAL1688 and BCAL1689

2.9

NS

BCAL1689

Mbt-like protein (orbH)

3.8

NS

BCAL1690

Dioxygenase (orbG)

2.3

NS

BCAL2192

Conserved hypothetical protein (iscX)

2.4

NS

BCAL2193

Ferredoxin (fdx)

2.5

NS

BCAL2194

Chaperone protein HscA homologue (hscA)

2.4

NS

BCAL2195

Chaperone protein HscB homologue (hscB)

2.3

NS

BCAL2196

Iron-sulfur cluster assembly protein (iscA)

1.6

NS

BCAL2197

Iron-sulfur cluster scaffold protein (iscU)

3.4

NS

BCAL2198

Cysteine desulfurase (iscS)

2.9

NS

BCAL2199

Transcriptional regulator protein (iscR)

2.3

NS

BCAL1105

Exported protein

6.8

12.7

BCAL1106

Cytochrome b561 family protein

4.1

8.3

BCAL1107

Oxidoreductase

2.7

3.4

BCAL3477

Putative catalase

2.7

NS

BCAL3478

Putative RNA polymerase σ factor

3.4

NS

  1. The results represent the fold change in gene expression in the treated biofilms compared to the gene expression in the untreated biofilms (based on the microarray analysis). NS: no significant change in expression was observed between the treated and the untreated biofilms (p > 0.05).