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Figure 1 | BMC Genomics

Figure 1

From: Analysis of deep sequencing microRNA expression profile from human embryonic stem cells derived mesenchymal stem cells reveals possible role of let-7 microRNA family in downstream targeting of Hepatic Nuclear Factor 4 Alpha

Figure 1

Different stages of processing microRNA sequences to gain biological insight. Massive sequencing data can be overwhelming to examine, with each stage of processing choices are made to direct analysis towards biological significance and understanding. Initial processing stages emphases on visualization of datasets in different forms such as annotations and alignment in the genome. This is to allow for quick assessment of salient features. Following this are more advanced analysis exploiting existing tools for examining distributions and networks topology to conjure biological hypothesis for verification. The entire workflow can then be thought as a funneling process towards biologically interesting interactions for verification in our hES-MSC cell line.

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BMC Genomics

ISSN: 1471-2164

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