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Table 3 Selected non-redundant survival-significant gene pairs identified in both cohorts of breast cancer patients

From: Complex sense-antisense architecture of TNFAIP1/POLDIP2 on 17q11.2 represents a novel transcriptional structural-functional gene module involved in breast cancer progression

Affymetrix U133 (A&B)

probeset

Gene Symbol

P value (individual)

Affyprobeset*

GS*

P value(individual)

P value(gene pair)

  

U

S

  

U

S

U

S

222425_s_at

POLDIP2

1.50E-05

0.024

A.201207_at

TNFAIP1

0.00011

0.081

3.10E-07

0.00046

201208_s_at

TNFAIP1

0.022

0.11

A.214283_at

TMEM97

0.074

0.081

0.00022

0.0029

213259_s_at

SARM1

0.011

0.074

B.225375_at

TMEM199

0.022

0.00072

0.00085

2.90E-05

204534_at

VTN

0.024

0.11

A.210312_s_at

IFT20

0.00041

0.024

0.00021

0.00052

204534_at

VTN

0.024

0.11

A.212279_at

TMEM97

0.0042

0.0035

1.00E-04

0.00062

210312_s_at

IFT20

0.00041

0.024

A.212281_s_at

TMEM97

0.0028

0.0051

1.60E-05

0.0036

213259_s_at

SARM1

0.011

0.074

A.212281_s_at

TMEM97

0.0028

0.0051

0.00039

0.004

217806_s_at

POLDIP2

4.30E-05

0.12

A.212281_s_at

TMEM97

0.0028

0.0051

2.60E-05

0.0036

225375_at

TMEM199

0.022

0.00072

A.201207_at

TNFAIP1

0.00011

0.081

9.30E-05

0.00021

225375_at

TMEM199

0.022

0.00072

A.212279_at

TMEM97

0.0042

0.0035

2.00E-04

0.00032

  1. Bold italics indicates gene pairs where the P values for a gene pair are at least ten times lower than that for either of the individual gene's of the pair for both the Uppsala and Stockholm cohorts. U, Uppsala cohort; S, Stockholm cohort.