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Table 5 Distribution of top 40 protein sequences containing at least two copies of EPIYA motif

From: Effector prediction in host-pathogen interaction based on a Markov model of a ubiquitous EPIYA motif

Protein Name

Number of proteins (number of genuses)

 

Total

Archaea

Viruses

Bacteria

Protista

Fungi

Metazoa

Viridiplantae

CagA

1015(1)

  

1015(1)

    

hypothetical protein

689(186)

15(10)

10(6)

242(88)

162(19)

78(28)

127(25)

55(11)

ATP*

81(21)

2(2)

 

68(11)

6(4)

4(3)

 

1(1)

Ankryin

55(7)

  

51(3)

  

4(4)

 

DNA*

52(34)

3(3)

 

40(25)

7(4)

1(1)

 

1(1)

Kinase

43(28)

5(2)

 

23(15)

4(3)

 

11(8)

 

zinc finger protein

43(11)

     

43(11)

 

TPR repeat protein

33(15)

  

33(15)

    

Polyprotein

24(2)

 

24(2)

     

SecA

23(14)

  

23(14)

    

Peptidase

19(12)

1(1)

 

16(9)

1(1)

 

1(1)

 

dynein heavy chain

17(13)

   

4(2)

1(1)

11(9)

1(1)

elongation factor 2

15(7)

   

10(2)

1(1)

4(4)

 

Palmdelphin

14(9)

     

14(9)

 

tRNA*

14(11)

2(1)

 

10(8)

1(1)

1(1)

  

glycogen synthase

13(1)

  

13(1)

    

GTP-binding

13(3)

  

12(2)

1(1)

   

transcriptional regulator

13(8)

1(1)

 

9(4)

 

3(3)

  

unc-119 homolog

13(6)

     

13(6)

 

FAT tumor suppressor homolog 3

12(9)

     

12(9)

 

nuclear ribonucleoprotein

12(9)

   

1(1)

10(7)

 

1(1)

4-alpha-glucanotransferase

9(1)

  

9(1)

    

paternally expressed 3

8(6)

     

8(6)

 

Striatin

8(7)

     

8(7)

 

Tarp

8(1)

  

8(1)

    

nuclear autoantigen

7(6)

     

7(6)

 

putative mannosyltransferase

7(1)

  

7(1)

    

Ubiquitin

7(6)

   

5(4)

2(2)

  

26S proteasome regulatory subunit

6(3)

      

6(3)

cell division protein

6(4)

3(3)

 

1(1)

    

centaurin, delta 3

6(5)

     

6(5)

 

fat tumor suppressor homolog 2

6(5)

     

6(5)

 

glycosyl transferase

6(5)

  

6(5)

    

guanine nucleotide exchange factor

6(6)

     

6(6)

 

cytochrome c oxidase subunit VI

5(4)

   

5(4)

   

PEG3

5(5)

     

5(5)

 

polyketide synthase

5(4)

  

3(3)

2(1)

   

polysaccharide biosynthesis protein

5(3)

  

5(3)

    

TatD-related deoxyribonuclease

5(1)

  

5(1)

    

translation initiation factor

5(4)

  

2(2)

2(1)

1(1)

  
  1. ATP* includes ATPase, ABC transporter, ATP-binding protein, and ATP-dependent helicase; DNA* includes DNA photolyase, DNA primase, DNA repair protein, DNA-binding protein, and DNA mismatch repair protein; kinases* includes histidine kinase, protein kinase, hexokinase, serine kinase, and fyn-related kinase; tRNA* includes tRNA synthetase, tRNA formyltransferase, and tRNA ligase.