Sample overview of full slide SOLiD runs. Figures 1A and 1B show panel average quality score distributions across two different full SOLiD slide runs. Black areas in four corners are regions not used by sequencing assay by design. Heat map scales are set up automatically according to the quality score range in each run. The pattern of low quality regions varies from run to run even in data from the same sequencing core. Figures 1C and 1D show the color code 0 percentage distribution and the genomic hit count distribution across different panels for the same sample illustrated in Fig. 1B, respectively. Numbers on the left and lower edge of each figure are the row and column number of panels. Numbers of the right side of the heat map scale bar are values associated with colors in the heatmap.