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Table 1 Gene Ontology (GO) categories over-represented in groups of responsive and non-responsive genes

From: Responsiveness of genes to manipulation of transcription factors in ES cells is associated with histone modifications and tissue specificity

Group of genes GO id GO name N genes p-value Enrichment ratio
Responsive genes with CpG islands GO:0048513 Organ development 543 0 2.233
  GO:0003700 Transcription factor 323 0 2.198
  GO:0007399 Nervous system devel. 268 0 2.351
  GO:0007155 Cell adhesion 211 0 2.032
  GO:0006928 Cell motility 134 6.6027E-12 2.095
  GO:0009888 Tissue development 125 1.0458E-13 2.322
  GO:0031012 Extracellular matrix 115 3.245E-11 2.175
  GO:0001568 Blood vessel devel. 107 0 3.313
  GO:0007507 Heart development 85 2.8866E-15 3.122
  GO:0016055 Wnt receptor signaling 60 1.1637E-10 3.008
Non-responsive genes with CpG islands GO:0015031 Protein transport 370 0 2.147
  GO:0006396 RNA processing 236 0 3.403
  GO:0006412 Translation 228 0 3.154
  GO:0044429 Mitochondrial part 206 4.4409E-16 2.475
  GO:0022403 Cell cycle phase 161 4.5759E-10 2.141
  GO:0016887 ATPase activity 158 1.3717E-10 2.278
  GO:0008380 RNA splicing 133 0 5.358
  GO:0006281 DNA repair 124 1.6187E-13 3.088
  GO:0006260 DNA replication 92 1.5896E-09 2.864
  GO:0006457 Protein folding 78 6.4245E-07 2.484