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Table 2 Cell wall related genes modulated in the ccw12 Δ transcriptional response

From: The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections

ORF

Gene

Description of gene product

Fold change(a)

   

Array

qRT-PCR

YBL001c

ECM15

Cell wall biogenesis and architecture

2.2

 

YBL043w

ECM13

Cell wall biogenesis and architecture

11.7

3.0 ± 0.9

YBL101c

ECM21

Cell wall biogenesis and architecture

2.4

 

YBR005w

RCR1

Protein of the ER membrane involved in cell wall chitin deposition

2.3

 

YBR023c

CHS3

Chitin synthase III

2.4

3.2 ± 0.7

YBR038w

CHS2

Chitin synthase II

2.3

 

YBR176w

ECM31

Cell wall biogenesis and architecture

2.5

 

YBR199w

KTR4

Putative mannosyltransferase

2.7

 

YBR205w

KTR3

alpha-1,2-mannosyltransferase

2.2

 

YBR229c

ROT2

Modification of N-linked oligosaccharides

2.3

 

YER011w

TIR1

Cell wall mannoprotein

0.4

 

YGL038c

OCH1

Modification of N-linked oligosaccharides

2.7

 

YGL259w

YPS5

Protein with similarity to GPI-anchored aspartic proteases

4.4

2.6 ± 0.1

YHR030c

SLT2

Serine/threonine MAP kinase

2.2

1.7 ± 0.1

YIL113w

SDP1

Dual-specificity MAP kinase phosphatase

4.4

 

YIR019c

MUC1

GPI-anchored cell surface glycoprotein (flocculin)

0.4

 

YIR039c

YPS6

Putative GPI-anchored aspartic protease

4.4

 

YJL095w

BCK1

Mitogen-activated protein (MAP) kinase kinase kinase

2.5

2.7 ± 0.5

YJL099w

CHS6

Mediate export of Chs3p from Golgi to PM

2.9

 

YJL128c

PBS2

MAP kinase kinase of the HOG pathway

3.7

 

YJL139c

YUR1

Mannosyltransferase of the KTR1 family

2.4

 

YJL174w

KRE9

beta-1,6 glucan assembly

2.5

 

YJR131w

MNS1

Alpha-1,2-mannosidase involved in N-linked glycosylation

2.1

 

YJR137c

ECM17

Cell wall biogenesis and architecture

3.2

 

YKL161c

MLP1

Putative ser/thr kinase with similarity to Slt2p

4.4

3.5 ± 0.3

YKL163w

PIR3

Cell wall mannoprotein

3.3

 

YKR076w

ECM4

Cell wall biogenesis and architecture

3.4

 

YLR121c

YPS3

GPI-anchored aspartic protease 3

2.9

 

YLR194c

YLR194C

GPI-anchored cell wall protein

3.2

 

YOL007c

CSI2

Structural component of the chitin synthase III complex

2.3

 

YOR382w

FIT2

GPI-anchored cell wall protein

3.3

 

YPL163c

SVS1

Cell wall and vacuolar protein

2.3

 
  1. (a) Data correspond to the ratio of expression of ccw12 versus wt calculated as described in "Methods".
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BMC Genomics

ISSN: 1471-2164

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