The genetic interaction network of CCW12, a Saccharomyces cerevisiae gene required for cell wall integrity during budding and formation of mating projections

Table 3 Mating related genes modulated in the ccw12 Δ transcriptional response

ORF	Gene	Description of gene product	Fold change^(a)
			Array	qRT-PCR
YBR040w	FIG1	Integral membrane protein required for efficient mating	0.4	0.3 ± 0.1
YCL027w	FUS1	Membrane protein localized to the shmoo tip, required for cell fusion	0.5	0.5 ± 0.1
YCR089w	FIG2	Cell wall adhesin, expressed specifically during mating	0.4
YDL039c	PRM7	Pheromone-regulated protein	0.4
YGL089c	MF(ALPHA)2	Mating pheromone alpha-factor	0.4
YIL117c	PRM5	Pheromone-regulated protein induced during cell integrity signalling	2.8
YJL108c	PRM10	Pheromone-regulated protein	3.7	2.4 ± 0.2
YML047c	PRM6	Pheromone-regulated protein	0.5
YNL279w	PRM1	Pheromone-regulated multispanning membrane protein	0.4
YNR044w	AGA1	Anchorage subunit of a-agglutinin of a-cells	0.4
YPL156c	PRM4	Pheromone-regulated protein	0.4
YPL192c	PRM3	Pheromone-regulated protein	0.3	0.7 ± 0.2

(a) Data correspond to the ratio of expression of ccw12 versus wt calculated as described in "Methods".

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