Ear swelling response in BALB/c mice. Percent (%) ear swelling was measured over time in BALB/c mice in response to BLG (n = 8), OVA (n = 8) or PNA (n = 8) sensitization and challenge (SC). Mice in the BLG, OVA and PNA SC groups indicated a significant ear swelling response when compared to that in PBS SC mice (n = 8) or mice in the BLG (n = 4), OVA (n = 4), PNA (n = 4) and PBS (n = 4) challenge (C) only groups. Results expressed as LSM ± standard error of the mean (SEM). *** represents p < 0.001.