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Table 7 Passive Cutaneous Anaphylaxis (PCA) assay in BALB/c mice. A blue wheal of a diameter of 3 mm or more, 30 min following challenge was considered as positive response and indicative of the presence of allergen-specific IgE. * p < 0.05

From: Mesenteric lymph node transcriptome profiles in BALB/c mice sensitized to three common food allergens

  Treatment Diameter (mm) Positive Reaction
Groups Sensitization Allergen Challenge Mean ± SEM (n) Responder/Total
  Naïve Serum PNA 0.9 ± 0.07 0/3
Naïve Control Naïve Serum OVA 0.8 ± 0.15 0/3
  Naïve Serum BLG 1.0 ± 0.03 0/3
  PBS SC Serum PNA 1.1 ± 0.13 0/3
PBS Control PBS SC Serum OVA 1.1 ± 0.21 0/3
  PBS SC Serum BLG 1.4 ± 0.26 0/3
Experimental Group 1 PNA SC Serum PNA 5.1 ± 0.43* 4/4
Experimental Group 2 OVA SC Serum OVA 4.5 ± 0.74* 3/4
Experimental Group 3 BLG SC Serum BLG 4.1 ± 0.72* 3/4