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Table 1 Significant KEGG identifiers detected based on the differentially expressed transcripts in cluster 1 for the acute phase response to E. col i infection*

From: In depth analysis of genes and pathways of the mammary gland involved in the pathogenesis of bovine Escherichia coli- mastitis

KEGG ID P value Odds Ratio Exp Count Count Size Term
4062 2.98E-09 5.571349 5.027606 22 106 Chemokine signaling pathway
4620 4.87E-06 6.066348 2.513803 12 53 Toll-like receptor signaling pathway
4670 2.71E-05 4.568835 3.414978 13 72 Leukocyte transendothelial migration
4060 9.62E-05 3.722762 4.363583 14 92 Cytokine-cytokine receptor interaction
4650 0.000254 4.473538 2.656094 10 56 Natural killer cell mediated cytotoxicity
4514 0.000518 3.714061 3.414978 11 72 Cell adhesion molecules (CAMs)
4622 0.000743 5.504747 1.565198 7 33 RIG-I-like receptor signaling pathway
4666 0.000873 4.103185 2.561233 9 54 Fc gamma R-mediated phagocytosis
4662 0.001521 4.767827 1.754919 7 37 B cell receptor signaling pathway
4612 0.002095 4.468453 1.84978 7 39 Antigen processing and presentation
4920 0.002438 4.332374 1.89721 7 40 Adipocytokine signaling pathway
4210 0.002843 3.718903 2.466373 8 52 Apoptosis
4610 0.00426 3.861615 2.086931 7 44 Complement and coagulation cascades
3050 0.00727 3.941793 1.754919 6 37 Proteasome
4630 0.00791 2.831847 3.509838 9 74 Jak-STAT signaling pathway
5340 0.008959 5.797582 0.853744 4 18 Primary immunodeficiency
564 0.046285 3.241129 1.375477 4 29 Glycerophospholipid metabolism
5200 0.04726 1.759624 7.778561 13 164 Pathways in cancer
  1. *A hypergeometric gene set enrichment test was performed based on cluster 1 of the contrast T24 vs. C24. Overrepresentation of gene sets defined by the KEGG database was tested using the Fisher's exact test. A gene set was considered significant if P < 0.05.